| PROKS, Vladimír, Josef JAROŠ, Ognen POP-GEORGIEVSKI, Jan KUČKA, Štěpán POPELKA, Petr DVOŘÁK, Aleš HAMPL and František RYPÁČEK. "Click & Seed" Approach to the Biomimetic Modification of Material Surfaces. Macromolecular Bioscience. Weinheim: Wiley-VCH Verlag, 2012, vol. 12, No 9, p. 1232-1242. ISSN 1616-5187. Available from: https://dx.doi.org/10.1002/mabi.201200095. |
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@article{1083511,
author = {Proks, Vladimír and Jaroš, Josef and PopandGeorgievski, Ognen and Kučka, Jan and Popelka, Štěpán and Dvořák, Petr and Hampl, Aleš and Rypáček, František},
article_location = {Weinheim},
article_number = {9},
doi = {http://dx.doi.org/10.1002/mabi.201200095},
keywords = {biomimetic modifications; click chemistry; peptide radiolabeling; polydopamine; poly(ethylene oxide)},
language = {eng},
issn = {1616-5187},
journal = {Macromolecular Bioscience},
title = {"Click & Seed" Approach to the Biomimetic Modification of Material Surfaces},
volume = {12},
year = {2012}
}
TY - JOUR
ID - 1083511
AU - Proks, Vladimír - Jaroš, Josef - Pop-Georgievski, Ognen - Kučka, Jan - Popelka, Štěpán - Dvořák, Petr - Hampl, Aleš - Rypáček, František
PY - 2012
TI - "Click & Seed" Approach to the Biomimetic Modification of Material Surfaces
JF - Macromolecular Bioscience
VL - 12
IS - 9
SP - 1232-1242
EP - 1232-1242
PB - Wiley-VCH Verlag
SN - 16165187
KW - biomimetic modifications
KW - click chemistry
KW - peptide radiolabeling
KW - polydopamine
KW - poly(ethylene oxide)
N2 - A simple, versatile, protein-repulsive, substrate-independent biomimetic surface modification is presented that is based on the creation of a PEO brush on a polydopamine anchoring layer and its capacity for selective follow-up modifications with various ligands using a coppercatalyzed alkyne-azide cycloaddition reaction. The desired surface concentration of peptide biomimetic ligands can be controlled by adjusting the peptide concentration in the reaction mixture, then measuring the activity of 125I-radiolabeled peptides that are immobilized on the substrates. The performance of the prepared substrates is tested in cell cultures with MEF cells and a human ECC line.
ER -
PROKS, Vladimír, Josef JAROŠ, Ognen POP-GEORGIEVSKI, Jan KUČKA, Štěpán POPELKA, Petr DVOŘÁK, Aleš HAMPL and František RYPÁČEK. ''Click \&{} Seed'' Approach to the Biomimetic Modification of Material Surfaces. \textit{Macromolecular Bioscience}. Weinheim: Wiley-VCH Verlag, 2012, vol.~12, No~9, p.~1232-1242. ISSN~1616-5187. Available from: https://dx.doi.org/10.1002/mabi.201200095.
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