KEJNOVSKÝ, Eduard, Monika MICHALOVOVÁ, Pavlína ŠTEFLOVÁ, Iva KEJNOVSKÁ, Susana MANZANO, Roman HOBZA, Zdeněk KUBÁT, Jan KOVAŘÍK, Manuel JAMILENA and Boris VYSKOT. Expansion of Microsatellites on Evolutionary Young Y Chromosome. PLoS One. San Francisco, CA, USA: Public Library of Science, 2013, vol. 8, No 1, p. "nestránkováno", 10 pp. ISSN 1932-6203. doi:10.1371/journal.pone.0045519.
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Basic information
Original name Expansion of Microsatellites on Evolutionary Young Y Chromosome
Authors KEJNOVSKÝ, Eduard (203 Czech Republic, guarantor, belonging to the institution), Monika MICHALOVOVÁ (203 Czech Republic), Pavlína ŠTEFLOVÁ (203 Czech Republic, belonging to the institution), Iva KEJNOVSKÁ (203 Czech Republic), Susana MANZANO (724 Spain), Roman HOBZA (203 Czech Republic), Zdeněk KUBÁT (203 Czech Republic, belonging to the institution), Jan KOVAŘÍK (203 Czech Republic), Manuel JAMILENA (724 Spain) and Boris VYSKOT (203 Czech Republic).
Edition PLoS One, San Francisco, CA, USA, Public Library of Science, 2013, 1932-6203.
Other information
Original language English
Type of outcome Article in a journal
Field of Study Genetics and molecular biology
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 3.534
RIV identification code RIV/00216224:14740/13:00067677
Organization unit Central European Institute of Technology
Doi http://dx.doi.org/10.1371/journal.pone.0045519
UT WoS 000313682700001
Keywords in English Chromosome; suppressed recombination; microsatellite expansion; transposable elements
Tags ok, rivok
Tags International impact, Reviewed
Changed by Changed by: Olga Křížová, učo 56639. Changed: 29/7/2013 11:59.
Abstract
Sex chromosomes are an ideal system to study processes connected with suppressed recombination. We found evidence of microsatellite expansion, on the relatively young Y chromosome of the dioecious plant sorrel (Rumex acetosa, XY1Y2 system), but no such expansion on the more ancient Y chromosomes of liverwort (Marchantia polymorpha) and human. The most expanding motifs were AC and AAC, which also showed periodicity of array length, indicating the importance of beginnings and ends of arrays. Our data indicate that abundance of microsatellites in genomes depends on the inherent expansion potential of specific motifs, which could be related to their stability and ability to adopt unusual DNA conformations. We also found that the abundance of microsatellites is higher in the neighborhood of transposable elements (TEs) suggesting that microsatellites are probably targets for TE insertions. This evidence suggests that microsatellite expansion is an early event shaping the Y chromosome where this process is not opposed by recombination, while accumulation of TEs and chromosome shrinkage predominate later.
Links
ED1.1.00/02.0068, research and development projectName: CEITEC - central european institute of technology
EE2.3.20.0045, research and development projectName: Podpora profesního růstu a mezinárodní integrace výzkumných týmů v oblasti molekulární medicíny
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