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JURÁK, Pavel, Václav ZVONÍČEK, Pavel LEINVEBER, Josef HALÁMEK and Vlastimil VONDRA. Respiratory induced heart rate and blood pressure variability during mechanical ventilation in critically ill and brain death patients. Online. In Lovell Nigel. 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Neuveden: Neuveden, 2012, p. 3821-3824. ISBN 978-1-4244-4119-8. Available from: https://dx.doi.org/10.1109/EMBC.2012.6346800.
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Basic information
Original name Respiratory induced heart rate and blood pressure variability during mechanical ventilation in critically ill and brain death patients
Authors JURÁK, Pavel (203 Czech Republic, guarantor), Václav ZVONÍČEK (203 Czech Republic, belonging to the institution), Pavel LEINVEBER (203 Czech Republic), Josef HALÁMEK (203 Czech Republic) and Vlastimil VONDRA (203 Czech Republic).
Edition Neuveden, 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, p. 3821-3824, 4 pp. 2012.
Publisher Neuveden
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 30201 Cardiac and Cardiovascular systems
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Publication form electronic version available online
RIV identification code RIV/00216224:14110/12:00058363
Organization unit Faculty of Medicine
ISBN 978-1-4244-4119-8
ISSN 1557-170X
Doi http://dx.doi.org/10.1109/EMBC.2012.6346800
UT WoS 000313296504012
Keywords in English Baroreflex; Blood pressure; Heart rate variability; Resonant frequency; TV; Ventilation
Tags International impact, Reviewed
Changed by Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 10/2/2013 16:46.
Abstract
We analysed respiratory induced heart rate and blood pressure variability in mechanically ventilated patients with different levels of sedation and central nervous system activity. Our aim was to determine whether it is possible to distinguish different levels of sedation or human brain activity from heart rate and blood pressure. We measured 19 critically ill and 15 brain death patients ventilated at various respiratory frequencies - 15, 12, 8 and 6 breaths per minute. Basal and deeper sedation was performed in the critically ill patients. We detected and analysed heart rate and blood pressure parameters induced by ventilation. Results: Respiratory induced heart rate variability is the unique parameter that can differentiate between brain death patients and sedated critically ill patients. Significant differences exist, especially during slow deep breathing with a mean period of 10 seconds. The limit values reflecting brain death are: baroreflex lower than 0.5 ms/mmHg and tidal volume normalised heart rate variability lower than 0.5 ms/ml. Reduced heart rate variability parameters of brain death patients remain unchanged even after normalisation to respiration volume. However, differences between basal and deep sedation do not appear significant on any parameter.
Links
GAP103/11/0933, research and development projectName: Analýza vysokofrekvenčního EEG signálu z hlubokých mozkových elektrod
Investor: Czech Science Foundation
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