DOLEŽALOVÁ, Irena, Robert KUBA, Klára MUSILOVÁ, Tomáš KAŠPÁREK, Milan BRÁZDIL and Ivan REKTOR. Neparaneoplastická limbická encefalitida s pozitivitou anit-LGI1 protilátek (Non-paraneoplastic limbic encephalitis with positivity of anti-LGI1 antibodies). Neurologie pro praxi. Olomouc: Solen, 2012, vol. 13, No 4, p. 221-224. ISSN 1213-1814.
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Basic information
Original name Neparaneoplastická limbická encefalitida s pozitivitou anit-LGI1 protilátek
Name (in English) Non-paraneoplastic limbic encephalitis with positivity of anti-LGI1 antibodies
Authors DOLEŽALOVÁ, Irena (203 Czech Republic, belonging to the institution), Robert KUBA (203 Czech Republic, guarantor, belonging to the institution), Klára MUSILOVÁ (203 Czech Republic, belonging to the institution), Tomáš KAŠPÁREK (203 Czech Republic, belonging to the institution), Milan BRÁZDIL (203 Czech Republic, belonging to the institution) and Ivan REKTOR (203 Czech Republic, belonging to the institution).
Edition Neurologie pro praxi, Olomouc, Solen, 2012, 1213-1814.
Other information
Original language Czech
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
WWW URL
RIV identification code RIV/00216224:14740/12:00063649
Organization unit Central European Institute of Technology
Keywords (in Czech) limbická encefalitida; paraneoplastická limbická encefalitida; neparaneoplastická limbická encefalitida; anti-LGI1 protilátky
Keywords in English limbic encephalitis; paraneoplastic limbic encephalitis; non-paraneoplastic limbic encephalitis; anti-LGI1 antibodies
Tags ok, rivok
Changed by Changed by: Olga Křížová, učo 56639. Changed: 16/4/2013 10:00.
Abstract
Limbická encefalitida (LE) je onemocnění postihující limbický systém, které se typicky projevuje poruchami paměti, nejvíce je postižena paměť recentní, současně se mohou objevit epileptické záchvaty a psychiatrické příznaky. Rozlišujeme paraneoplastickou (PLE) a neparaneoplastickou (NLE) limbickou encefalitidu. Recentně byla popsána asociace NLE s anti-LGI1 protilátkami. Uvádíme případ 45leté pacientky s LE a pozitivitou anti-LGI1 protilátek. V článku se věnujeme i diferenciální diagnóze a terapii tohoto onemocnění.
Abstract (in English)
Limbic encephalitis (LE) is a condition affecting the limbic system that typically presents with memory disorders, with recent memory being most affected; concurrently, epileptic seizures and psychiatric symptoms can occur. Paraneoplastic limbic encephalitis (PLE) and non-paraneoplastic limbic encephalitis (NLE) are distinguished. Recently, an association of NLE with anti-LGI1 antibodies has been described. We report a case of a 45-year-old female patient with LE and positivity of anti-LGI1 antibodies. The differential diagnosis and treatment of this disease are also discussed.
Links
ED1.1.00/02.0068, research and development projectName: CEITEC - central european institute of technology
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