Endoscopic third ventriculostomy to treat hydrocephalus in children with brain tumours - a single centre experience

VENTRUBA, Jiří, Zdeněk MACKERLE, Karel ZITTERBART and Jaroslav ŠTĚRBA. Endoscopic third ventriculostomy to treat hydrocephalus in children with brain tumours - a single centre experience (Endoscopic Third Ventriculostomy to Treat Hydrocephalus in Children with Brain Tumours - a Single Centre Experience). CESKA A SLOVENSKA NEUROLOGIE A NEUROCHIRURGIE. Praha: ČLS JEP, 2012, vol. 75, No 2, p. 212-217. ISSN 1210-7859.

Basic information

• Original name: Endoscopic third ventriculostomy to treat hydrocephalus in children with brain tumours - a single centre experience
• Name in Czech: Endoskopická ventrikulostomie III. komory v léčbě hydrocefalu u dětí s mozkovými tumory- zkušenosti jednoho centra
• Name (in English): Endoscopic Third Ventriculostomy to Treat Hydrocephalus in Children with Brain Tumours - a Single Centre Experience
• Authors: VENTRUBA, Jiří, Zdeněk MACKERLE, Karel ZITTERBART and Jaroslav ŠTĚRBA.
• Edition: CESKA A SLOVENSKA NEUROLOGIE A NEUROCHIRURGIE, Praha, ČLS JEP, 2012, 1210-7859.

Other information

• Original language: Czech
• Type of outcome: Article in a journal
• Field of Study: 30200 3.2 Clinical medicine
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• Impact factor: Impact factor: 0.372
• Organization unit: Faculty of Medicine
• UT WoS: 000303294000012
• Keywords (in Czech): Endoskopická III. ventrikulostomie; hydrocefalus; tumor mozku; dětská onkologie
• Keywords in English: endoscopic third ventriculostomy; hydrocephalus; brain tumour; paediatric oncology

Abstract

Neuroendoskopie je miniinvazivní alternativou především implantace drenážních systémů. V indikovaných případech od ní lze očekávat výrazné snížení morbidity a zlepšení kvality života dětí s mozkovými nádory. U dětí s tumorem zadní jámy lební může neuroendoskopická. ventrikulostomie III. komory nahradit implantaci vnitřního drenážního systému. U obtížně přístupných nitrokomorových expanzí je možné zpřesnit diagnózu endoskopickým odběrem biopsie a v jedné době provést i definitivní ošetření sekundárního hydrocefalu.

Abstract (in English)

Neuroendoscopy is a mini-invasive alternative to implantation of drainage systems in particular. In indicated cases, this method could lower morbidity and increase the quality of life in children with brain tumours. In children with a tumour of posterior fossa, endoscopic third ventriculostomy (ETV) could be used instead of internal drainage system implantation. In patients with deep-seated intraventricular expansions, the diagnosis may be refined using endoscopic sample biopsy and, simultaneously, definitive treatment can be provided of the secondary hydrocephalus. Aim: To obtain short-term outcome data for endoscopic treatment of hydrocephalus in children with brain tumours in a tertiary care centre and to evaluate reliability of this approach. Patients and method: The sample involved 21 children, 16 boys and 5 girls, aged 1 to 16 years with a primary brain tumour and secondary obstructive hydrocephalus caused by the tumour who underwent surgery between 1st January 2008 and the end of November 2010. Results: Six patients had no permanent cerebral spinal fluid (CSF) drainage after the brain tumour surgery, other 5 had a successful ETV, 10 children had a permanent ventricular-peritoneal shunt (V-P) implanted (2 of them after an unsuccessful ETV). The length of the procedure for hydrocephalus itself is comparable between shunt and ETV. Nevertheless, the length of primary hospitalization is markedly shorter for the patients with ETV (28 das versus 41 days for patients with V-P shunt). Likewise, complications demanding further surgical revisions were more frequent in patients with implanted drainage system. Conclusion: The miniinvasive endoscopic approach was included in our therapeutic algorithm as the method of choice to treat secondary hydrocephalus in children with posterior fossa tumour. Implantation of an internal drainage system is the second line approach in patients in whom ETV cannot be performed or fails.