RYZÍ, Michal, Milan BRÁZDIL, Zdeněk NOVÁK, Jan CHRASTINA, Hana OŠLEJŠKOVÁ, Ivan REKTOR and Robert KUBA. Long-term vagus nerve stimulation in children with focal epilepsy. ACTA NEUROLOGICA SCANDINAVICA. MALDEN, USA: WILEY-BLACKWELL, 2013, vol. 127, No 5, p. 316-322. ISSN 0001-6314. Available from: https://dx.doi.org/10.1111/ane.12009. |
Other formats:
BibTeX
LaTeX
RIS
@article{1087789, author = {Ryzí, Michal and Brázdil, Milan and Novák, Zdeněk and Chrastina, Jan and Ošlejšková, Hana and Rektor, Ivan and Kuba, Robert}, article_location = {MALDEN, USA}, article_number = {5}, doi = {http://dx.doi.org/10.1111/ane.12009}, keywords = {child neurology; epilepsy; quality of life; seizures; treatment}, language = {eng}, issn = {0001-6314}, journal = {ACTA NEUROLOGICA SCANDINAVICA}, title = {Long-term vagus nerve stimulation in children with focal epilepsy}, volume = {127}, year = {2013} }
TY - JOUR ID - 1087789 AU - Ryzí, Michal - Brázdil, Milan - Novák, Zdeněk - Chrastina, Jan - Ošlejšková, Hana - Rektor, Ivan - Kuba, Robert PY - 2013 TI - Long-term vagus nerve stimulation in children with focal epilepsy JF - ACTA NEUROLOGICA SCANDINAVICA VL - 127 IS - 5 SP - 316-322 EP - 316-322 PB - WILEY-BLACKWELL SN - 00016314 KW - child neurology KW - epilepsy KW - quality of life KW - seizures KW - treatment N2 - Objectives – The aim of the study was to evaluate the long-term efficacy and hospitalization rates in children with refractory focal epilepsy treated by vagus nerve stimulation. Materials and methods – We retrospectively analyzed 15 children with intractable focal epilepsy treated by vagus nerve stimulation (mean age of 14.6 +/- 2.5 years at the time of implantation). We analyzed the treatment effectiveness at 1, 2, and 5 year follow-up visits. We counted the average number of urgent hospitalizations and number of days of urgent hospitalization per year for each patient before and after the VNS implantation. Results – The mean seizure reduction was 42.5% at 1 year, 54.9% at 2 years, and 58.3% at 5 years. The number of responders was 7 (46.7%) at 1 year and 9 (60%) at both 2 and 5 years. The mean number of urgent hospitalizations per patient was 1.0 +/- 0.6 per year preoperatively and 0.3 +/- 0.5 per year post-operatively. The mean number of days of urgent hospitalization per patient was 9.3 +/- 6.1 per year preoperatively and 1.3 +/- 1.8 per year postoperatively. Conclusions – Vagus nerve stimulation is an effective method of treating children with refractory focal epilepsy. It leads to a substantial decrease in the number and duration of urgent hospitalizations. ER -
RYZÍ, Michal, Milan BRÁZDIL, Zdeněk NOVÁK, Jan CHRASTINA, Hana OŠLEJŠKOVÁ, Ivan REKTOR and Robert KUBA. Long-term vagus nerve stimulation in children with focal epilepsy. \textit{ACTA NEUROLOGICA SCANDINAVICA}. MALDEN, USA: WILEY-BLACKWELL, 2013, vol.~127, No~5, p.~316-322. ISSN~0001-6314. Available from: https://dx.doi.org/10.1111/ane.12009.
|