Novel pH dependent lectin from bioluminescent bacterium Photorhabdus luminescens

SÝKOROVÁ, Petra, Pavel DOBEŠ, Pavel HYRŠL and Michaela WIMMEROVÁ. Novel pH dependent lectin from bioluminescent bacterium Photorhabdus luminescens. 2012.

Basic information

• Original name: Novel pH dependent lectin from bioluminescent bacterium Photorhabdus luminescens
• Authors: SÝKOROVÁ, Petra (203 Czech Republic, belonging to the institution), Pavel DOBEŠ (203 Czech Republic, belonging to the institution), Pavel HYRŠL (203 Czech Republic, belonging to the institution) and Michaela WIMMEROVÁ (203 Czech Republic, guarantor, belonging to the institution).
• Edition: 2012.

Other information

• Original language: English
• Type of outcome: Conference abstract
• Field of Study: 10600 1.6 Biological sciences
• Country of publisher: United States of America
• Confidentiality degree: is not subject to a state or trade secret
• RIV identification code: RIV/00216224:14310/12:00058567
• Organization unit: Faculty of Science
• UT WoS: 000310368700390
• Keywords in English: Photorhabdus luminescens; lectins

Abstract

Lectins are capable of specific and reversible binding to carbohydrate moieties and are able to agglutinate cells. Carbohydrate-mediated recognition plays an important role in the ability of pathogenic bacteria to adhere to the surface of the host cell in the first step of their invasion and infectivity. The contribution is focused on characterization of the lectin from Gram-negative bacterium Photorhabdus luminescens, especially on determination of the function properties. Photorhabdus luminescens is a Gram-negative bacterium that is mutualistically associated with entomopathogenic nematodes from the genera Heterorhabditis. These nematodes infect the insect in larvae stage and release the bacteria into insect blood.

Links

• GA303/09/1168, research and development project: Name: Lektiny z lidských patogenů - struktura, funkce, inženýrství

Investor: Czech Science Foundation, Lectins from human pathogens - structure, function, engineering

• GD301/09/H004, research and development project: Name: Molekulární a strukturní biologie vybraných cytostatik. Od mechanistických studií k chemoterapii rakoviny

Investor: Czech Science Foundation

• QJ1210047, research and development project: Name: Vývoj nových prostředků pro podporu imunity včel, prevenci a léčbu včelích onemocnění (Acronym: Probiotika - imunita včel)

Investor: Ministry of Agriculture of the CR