Origin and evolution of genes and genomes. Crucial role of triplet expansions

TRIFONOV, Eduard Nikolajevič and Zakharia M FRENKEL. Origin and evolution of genes and genomes. Crucial role of triplet expansions. J. Biomol. Struct. Dynamics 12. Philadelphia: Taylor&Francis Inc., 2012, vol. 30, No 2, p. 201-210. ISSN 0739-1102. Available from: https://dx.doi.org/10.1080/07391102.2012.677771.

Basic information

• Original name: Origin and evolution of genes and genomes. Crucial role of triplet expansions
• Authors: TRIFONOV, Eduard Nikolajevič (376 Israel, guarantor, belonging to the institution) and Zakharia M FRENKEL (376 Israel).
• Edition: J. Biomol. Struct. Dynamics 12, Philadelphia, Taylor&Francis Inc. 2012, 0739-1102.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: Genetics and molecular biology
• Country of publisher: United States of America
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• Impact factor: Impact factor: 4.986 in 2010
• RIV identification code: RIV/00216224:14740/12:00064280
• Organization unit: Central European Institute of Technology
• Doi: http://dx.doi.org/10.1080/07391102.2012.677771
• UT WoS: 000305255800007
• Keywords in English: triplet expansion; repeats; codon usage; gene evolution
• Tags: ok, rivok
• Tags: International impact

Abstract

A novel concept on mechanisms of evolution of genes and genomes is suggested: the sequences evolve largely by local events of triplet expansion and subsequent mutational changes in the repeats.Life which, presumably, started with replication of expanding triplets and their subsequent mutational changes, is continuing to emerge within the genes and genomes, in form of new events of triplet expansion.

Links

• ED1.1.00/02.0068, research and development project: Name: CEITEC - central european institute of technology
• SIGA 792, interní kód MU: Name: CHROMPLANT

Investor: South-Moravian Region, Incoming grants