Origin and evolution of genes and genomes. Crucial role of triplet expansions

TRIFONOV, Eduard Nikolajevič and Zakharia M FRENKEL. Origin and evolution of genes and genomes. Crucial role of triplet expansions. J. Biomol. Struct. Dynamics 12. Philadelphia: Taylor&Francis Inc., 2012, vol. 30, No 2, p. 201-210. ISSN 0739-1102. Available from: https://dx.doi.org/10.1080/07391102.2012.677771.

Basic information

Original name

Origin and evolution of genes and genomes. Crucial role of triplet expansions

Authors

TRIFONOV, Eduard Nikolajevič (376 Israel, guarantor, belonging to the institution) and Zakharia M FRENKEL (376 Israel)

Edition

J. Biomol. Struct. Dynamics 12, Philadelphia, Taylor&Francis Inc. 2012, 0739-1102

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Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

Genetics and molecular biology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 4.986 in 2010

RIV identification code

RIV/00216224:14740/12:00064280

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1080/07391102.2012.677771

UT WoS

000305255800007

Keywords in English

triplet expansion; repeats; codon usage; gene evolution

Tags

ok, rivok

Tags

International impact

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Abstract

V originále

A novel concept on mechanisms of evolution of genes and genomes is suggested: the sequences evolve largely by local events of triplet expansion and subsequent mutational changes in the repeats.Life which, presumably, started with replication of expanding triplets and their subsequent mutational changes, is continuing to emerge within the genes and genomes, in form of new events of triplet expansion.

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Links

ED1.1.00/02.0068, research and development project	Name: CEITEC - central european institute of technology
SIGA 792, interní kód MU	Name: CHROMPLANT Investor: South-Moravian Region, Incoming grants