J 2012

Apoptotic cleavage of DNA in human lymphocyte chromatin shows high sequence specificity

BETTECKEN, Thomas, Zakharia M FRENKEL, Janine ALTMUELLER, Peter NUERNBERG, Eduard Nikolajevič TRIFONOV et. al.

Basic information

Original name

Apoptotic cleavage of DNA in human lymphocyte chromatin shows high sequence specificity

Authors

BETTECKEN, Thomas (276 Germany), Zakharia M FRENKEL (376 Israel), Janine ALTMUELLER (276 Germany), Peter NUERNBERG (276 Germany) and Eduard Nikolajevič TRIFONOV (376 Israel, guarantor, belonging to the institution)

Edition

J. Biomol. Struct. Dynamics, Philadelphia, Taylor&Francis Inc. 2012, 0739-1102

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

Genetics and molecular biology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 4.986 in 2010

RIV identification code

RIV/00216224:14740/12:00064282

Organization unit

Central European Institute of Technology

UT WoS

000305255800008

Keywords in English

apoptosis; DNA fragmentation; apoptotic ladder; nucleosome

Tags

Tags

International impact, Reviewed
Změněno: 9/4/2013 15:29, Olga Křížová

Abstract

V originále

Apoptotic digestion of human lymphocyte chromatin results in the appearance of large amounts of nucleosome size DNA fragments.his consensus also possesses three TA dinucleotide steps, separated by five bases (corresponding to a half-period of the DNA double helix), suggesting strong bending of the DNA at the cut sites which is perhaps required for cutting.

Links

MSM0021622415, plan (intention)
Name: Molekulární podstata buněčných a tkáňových regulací
Investor: Ministry of Education, Youth and Sports of the CR, Molecular basis of cell and tissue regulations
SIGA 792, interní kód MU
Name: CHROMPLANT
Investor: South-Moravian Region, Incoming grants