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@proceedings{1091894,
author = {Houser, Josef and Matuška, Radek and Kozmon, Stanislav and Romano, Patric and Koča, Jaroslav and Wimmerová, Michaela},
booktitle = {11th Discussions in Structural Molecular Biology},
keywords = {lectin; Aleuria aurantia; structure analysis},
language = {eng},
title = {The power is in detail - Structural analysis of an Aleuria aurantia lectin mutant},
year = {2013}
}
TY - CONF
ID - 1091894
AU - Houser, Josef - Matuška, Radek - Kozmon, Stanislav - Romano, Patric - Koča, Jaroslav - Wimmerová, Michaela
PY - 2013
TI - The power is in detail - Structural analysis of an Aleuria aurantia lectin mutant
KW - lectin
KW - Aleuria aurantia
KW - structure analysis
N2 - We have crystallized one AAL mutant that has been proved to have stronger affinity towards a1-6 bound fucose. We were able to collect several datasets of high quality with resolution up to 1.09A. The detailed insight into the structure revealed the principal of the affinity change, shading the light upon variability of AAL’s binding sites differences. Furthermore, we utilized in silico approach to describe the contribution of particular amino acids in each of five AAL's binding sites.
ER -
HOUSER, Josef, Radek MATUŠKA, Stanislav KOZMON, Patric ROMANO, Jaroslav KOČA and Michaela WIMMEROVÁ. The power is in detail - Structural analysis of an Aleuria aurantia lectin mutant. In \textit{11th Discussions in Structural Molecular Biology}. 2013. ISSN~1211-5894.
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