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@article{1092036,
author = {Krejčí, Pavel and Mekikian, PB and Wilcox, WR},
article_number = {6},
doi = {http://dx.doi.org/10.1038/sj.leu.2404202},
keywords = {FACTOR RECEPTOR-3; EXPRESSION; MUTATIONS},
language = {eng},
issn = {0887-6924},
journal = {Leukemia},
title = {The fibroblast growth factors in multiple myeloma},
url = {http://www.nature.com/leu/journal/v20/n6/full/2404202a.html},
volume = {20},
year = {2006}
}
TY - JOUR
ID - 1092036
AU - Krejčí, Pavel - Mekikian, PB - Wilcox, WR
PY - 2006
TI - The fibroblast growth factors in multiple myeloma
JF - Leukemia
VL - 20
IS - 6
SP - 1165-1168
EP - 1165-1168
SN - 08876924
KW - FACTOR RECEPTOR-3
KW - EXPRESSION
KW - MUTATIONS
UR - http://www.nature.com/leu/journal/v20/n6/full/2404202a.html
L2 - http://www.nature.com/leu/journal/v20/n6/full/2404202a.html
N2 - Fibroblast growth factor receptor 3 (FGFR3) is a membrane-anchored receptor tyrosine kinase that transmits intercellular signals mediated by a family of fibroblast growth factors (FGFs). In multiple myeloma (MM), 15% of patients markedly upregulate FGFR3 as a consequence of a t(4;14)(p16.3;q32) translocation. Ectopic expression of FGFR3 enhances MM cell proliferation and survival, demonstrating the oncogenic potential of FGFR3.
ER -
KREJČÍ, Pavel, PB MEKIKIAN a WR WILCOX. The fibroblast growth factors in multiple myeloma. \textit{Leukemia}. roč.~20, č.~6, s.~1165-1168. ISSN~0887-6924. doi:10.1038/sj.leu.2404202. 2006.
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