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@proceedings{1104696,
author = {Beneš, Petr and Navrátilová, Jarmila and Hankeová, Tereza and Nehybová, Tereza and Knopfová, Lucia and Šmarda, Jan},
booktitle = {The 9th Symposium on Molecular Pathology and Histo(cyto)chemistry},
keywords = {disulfiram; breast cancer; wedelolactone; tumor microenvironment; cytotoxicity},
language = {eng},
isbn = {978-80-7471-022-3},
title = {Specific conditions of tumor microenvironment enhance cytotoxicity of disulfiram, tetrathiomolybdate and wedelolactone to breast cancer and neuroblastoma cells},
year = {2013}
}
TY - CONF
ID - 1104696
AU - Beneš, Petr - Navrátilová, Jarmila - Hankeová, Tereza - Nehybová, Tereza - Knopfová, Lucia - Šmarda, Jan
PY - 2013
TI - Specific conditions of tumor microenvironment enhance cytotoxicity of disulfiram, tetrathiomolybdate and wedelolactone to breast cancer and neuroblastoma cells
SN - 9788074710223
KW - disulfiram
KW - breast cancer
KW - wedelolactone
KW - tumor microenvironment
KW - cytotoxicity
N2 - Our study was designed to analyze the effects of hypoxia, acidosis, and limited glucose supply to cytotoxicity of disulfiram, tetrathiomolybdate and wedelolactone to breast cancer and neuroblastoma cells. We found that cytotoxicity of these drugs can be strongly enhanced by manipulating tissue culture conditions that simulate the character of tumor microenvironment.
ER -
BENEŠ, Petr, Jarmila NAVRÁTILOVÁ, Tereza HANKEOVÁ, Tereza NEHYBOVÁ, Lucia KNOPFOVÁ a Jan ŠMARDA. Specific conditions of tumor microenvironment enhance cytotoxicity of disulfiram, tetrathiomolybdate and wedelolactone to breast cancer and neuroblastoma cells. In \textit{The 9th Symposium on Molecular Pathology and Histo(cyto)chemistry}. 2013. ISBN~978-80-7471-022-3.
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