Detailed Information on Publication Record
2013
The role of microRNAs in mitochondria in cancer
BIENERTOVÁ VAŠKŮ, Julie, Jiří ŠÁNA and Ondřej SLABÝBasic information
Original name
The role of microRNAs in mitochondria in cancer
Authors
BIENERTOVÁ VAŠKŮ, Julie (203 Czech Republic, belonging to the institution), Jiří ŠÁNA (203 Czech Republic, belonging to the institution) and Ondřej SLABÝ (203 Czech Republic, guarantor, belonging to the institution)
Edition
Cancer Letters, OXFORD, ELSEVIER, 2013, 0304-3835
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30200 3.2 Clinical medicine
Country of publisher
Ireland
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 5.016
RIV identification code
RIV/00216224:14740/13:00065603
Organization unit
Central European Institute of Technology
UT WoS
000321477800001
Keywords in English
microRNA; mitochondria; Krebs cycle; apoptosis; mitophagy
Tags
Tags
International impact, Reviewed
Změněno: 5/4/2014 17:13, Olga Křížová
Abstract
V originále
Reprogramming of the energy metabolism in cancer cell presents progressive field of cancer research. This feature is associated mainly with the mitochondria, which is major energy source of eukaryotic cells. These organelles are essential to the cell homeostasis maintenance, play an important role in intrinsic apoptotic pathway and their dysfunction is associated with multiple diseases including cancer. Recently, it was described that microRNAs (miRNAs) regulate important signaling pathways in mitochondria and many of these miRNAs are deregulated in various cancers. Here we summarize current knowledge about miRNAs involved in mitochondrial functioning with focus on cellular energy metabolism, apoptosis and mitophagy.
Links
| ED1.1.00/02.0068, research and development project |
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| NT13514, research and development project |
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