SVOBODA, David and Vladimír ULMAN. Towards a Realistic Distribution of Cells in Synthetically Generated 3D Cell Populations. In Alfredo Petrosino. 17th International Conference on Image Analysis and Processing - ICIAP 2013. LNCS 8157, Part II. Berlin, Heidelberg: Springer-Verlag, 2013, p. 429-438. ISBN 978-3-642-41183-0. Available from: https://dx.doi.org/10.1007/978-3-642-41184-7_44.
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Basic information
Original name Towards a Realistic Distribution of Cells in Synthetically Generated 3D Cell Populations
Authors SVOBODA, David (203 Czech Republic, guarantor, belonging to the institution) and Vladimír ULMAN (203 Czech Republic, belonging to the institution).
Edition LNCS 8157, Part II. Berlin, Heidelberg, 17th International Conference on Image Analysis and Processing - ICIAP 2013, p. 429-438, 10 pp. 2013.
Publisher Springer-Verlag
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 20200 2.2 Electrical engineering, Electronic engineering, Information engineering
Country of publisher Italy
Confidentiality degree is not subject to a state or trade secret
Publication form storage medium (CD, DVD, flash disk)
Impact factor Impact factor: 0.402 in 2005
RIV identification code RIV/00216224:14330/13:00066208
Organization unit Faculty of Informatics
ISBN 978-3-642-41183-0
ISSN 0302-9743
Doi http://dx.doi.org/10.1007/978-3-642-41184-7_44
UT WoS 000329811200044
Keywords in English cell populations; simulation; cross-correlation
Tags CBIA, cbia-web, firank_B
Tags International impact, Reviewed
Changed by Changed by: doc. RNDr. David Svoboda, Ph.D., učo 2824. Changed: 12/9/2014 13:41.
Abstract
In fluorescence microscopy, the proper evaluation of image segmentation algorithms is still an open problem. In the field of cell segmentation, such evaluation can be seen as a study of the given algorithm how well it can discover individual cells as a function of the number of them in an image (size of cell population), their mutual positions (density of cell clusters), and the level of noise. Principally, there are two approaches to the evaluation. One approach requires real input images and an expert that verifies the segmentation results. This is, however, expert dependent and, namely when handling 3D data, very tedious. The second approach uses synthetic images with ground truth data to which the segmentation result is compared objectively. In this paper, we propose a new method for generating synthetic 3D images showing naturally distributed cell populations attached to microscope slide. Cell count and clustering probability are user parameters of the method.
Links
GBP302/12/G157, research and development projectName: Dynamika a organizace chromosomů během buněčného cyklu a při diferenciaci v normě a patologii
Investor: Czech Science Foundation
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