KLEMENT, Matej, David ŠAFRÁNEK, Tadeáš DĚD, Aleš PEJZNOCH, Ladislav NEDBAL, Ralf STEUER, Jan ČERVENÝ and Stefan MUELLER. A Comprehensive Web-based Platform For Domain-Specific Biological Models. Online. In Proceedings of the fourth International Workshop on Interactions between Computer Science and Biology (CS2Bio'13). Neuveden: Elsevier, 2013, p. 61-67. ISSN 1571-0661. Available from: https://dx.doi.org/10.1016/j.entcs.2013.11.006.
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Basic information
Original name A Comprehensive Web-based Platform For Domain-Specific Biological Models
Authors KLEMENT, Matej (703 Slovakia, belonging to the institution), David ŠAFRÁNEK (203 Czech Republic, guarantor, belonging to the institution), Tadeáš DĚD (203 Czech Republic, belonging to the institution), Aleš PEJZNOCH (203 Czech Republic, belonging to the institution), Ladislav NEDBAL (203 Czech Republic), Ralf STEUER (276 Germany), Jan ČERVENÝ (203 Czech Republic) and Stefan MUELLER (40 Austria).
Edition Neuveden, Proceedings of the fourth International Workshop on Interactions between Computer Science and Biology (CS2Bio'13), p. 61-67, 7 pp. 2013.
Publisher Elsevier
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 10201 Computer sciences, information science, bioinformatics
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Publication form electronic version available online
WWW URL
RIV identification code RIV/00216224:14330/13:00068771
Organization unit Faculty of Informatics
ISSN 1571-0661
Doi http://dx.doi.org/10.1016/j.entcs.2013.11.006
UT WoS 000216920700006
Keywords in English systems biology; modelling; mode repository; database
Tags International impact, Reviewed
Changed by Changed by: RNDr. Pavel Šmerk, Ph.D., učo 3880. Changed: 24/4/2014 18:17.
Abstract
A Comprehensive Modeling Platform, that is, a general framework for public sharing, annotation, and visualization of domain-specific biological models, is presented. For a selected organism, the framework is instantiated as a web-based application which allows to capture several aspects of biological models represented as biochemical reaction networks or ordinary differential equations. The key feature of the instantiation for a given organism relies on mapping kinetic models to a precise textual and a schematic graphical representation of the related biological knowledge, thereby supporting the systems biological view of the modeled organism. Besides model repository and annotation, the platform includes basic model analysis features such as simulation and static analysis.
Links
EE2.3.20.0256, research and development projectName: Vytvoření výzkumného týmu a mezinárodního konzorcia pro počítačový model buňky sinice
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