PAI, Madhava, Vlastimil VÁLEK, Tomáš ANDRAŠINA, Attila DOROS, Pietro QUARETTI, Rita GOLFIERI, Cristina MOSCONI and Habib NAGY. Percutaneous Intraductal Radiofrequency Ablation for Clearance of Occluded Metal Stent in Malignant Biliary Obstruction: Feasibility and Early Results. CardioVascular and Interventional Radiology. New York: Springer-Verlag, 2014, vol. 37, No 1, p. 235-240. ISSN 0174-1551. Available from: https://dx.doi.org/10.1007/s00270-013-0688-x.
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Basic information
Original name Percutaneous Intraductal Radiofrequency Ablation for Clearance of Occluded Metal Stent in Malignant Biliary Obstruction: Feasibility and Early Results
Authors PAI, Madhava (826 United Kingdom of Great Britain and Northern Ireland), Vlastimil VÁLEK (203 Czech Republic, belonging to the institution), Tomáš ANDRAŠINA (703 Slovakia, guarantor, belonging to the institution), Attila DOROS (348 Hungary), Pietro QUARETTI (380 Italy), Rita GOLFIERI (380 Italy), Cristina MOSCONI (380 Italy) and Habib NAGY (840 United States of America).
Edition CardioVascular and Interventional Radiology, New York, Springer-Verlag, 2014, 0174-1551.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 2.071
RIV identification code RIV/00216224:14110/14:00074725
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1007/s00270-013-0688-x
UT WoS 000329994100029
Keywords in English Bile duct/gallbladder/biliary; Cancer; Interventional oncology; Liver/hepatic; Pancreas; Radiofrequency ablation; Stenosis/restenosis; Tumour/neoplasm
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 24/4/2015 12:35.
Abstract
Purpose: The major complication occurring with biliary stents is stent occlusion, frequently seen because of tumour in-growth, epithelial hyperplasia, and sludge deposits, resulting in recurrent jaundice and cholangitis. We report a prospective study with the results of first in man percutaneous intraductal radiofrequency (RF) ablation to clear the blocked metal stents in patients with malignant biliary obstruction using a novel bipolar RF catheter. Methods: Nine patients with malignant biliary obstruction and blocked metal stents were included. These patients underwent intraductal biliary RF ablation through the blocked metal stent following external biliary decompression with an internal-external biliary drainage. Results: All nine patients had their stent patency restored successfully without the use of secondary stents. Following this intervention, there was no 30-day mortality, haemorrhage, bile duct perforation, bile leak, or pancreatitis. Of the nine patients, six are alive and three patients are dead with a median follow-up of 122 (range 50-488) days and a median stent patency of 102.5 (range 50-321) days. Six patients had their stent patent at the time of last follow-up or death. Three patients with stent blockage at 321, 290, and 65 days postprocedure underwent percutaneous transhepatic drain insertion and repeat ablation. Conclusions: In this selective group of patients, it appears that this new approach is safe and feasible. Efficacy remains to be proven in future, randomized, prospective studies.
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