Hippocampal negative event-related potential recorded in humans
during a simple sensorimotor task occurs independently of motor
execution

J 2013

Hippocampal negative event-related potential recorded in humans during a simple sensorimotor task occurs independently of motor execution

ROMAN, Robert, Milan BRÁZDIL, Jan CHLÁDEK, Ivan REKTOR, Pavel JURÁK et. al.

Basic information

Original name

Hippocampal negative event-related potential recorded in humans during a simple sensorimotor task occurs independently of motor execution

Authors

ROMAN, Robert (203 Czech Republic, belonging to the institution), Milan BRÁZDIL (203 Czech Republic, guarantor, belonging to the institution), Jan CHLÁDEK (203 Czech Republic, belonging to the institution), Ivan REKTOR (203 Czech Republic, belonging to the institution), Pavel JURÁK (203 Czech Republic), Miroslav SVĚTLÁK (203 Czech Republic, belonging to the institution), Alena DAMBORSKÁ (203 Czech Republic, belonging to the institution), Daniel Joel SHAW (826 United Kingdom of Great Britain and Northern Ireland, belonging to the institution) and Miloslav KUKLETA (203 Czech Republic, belonging to the institution)

Edition

Hippocampus, Hoboken, USA, WILEY-BLACKWELL, 2013, 1050-9631

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 4.302

RIV identification code

RIV/00216224:14740/13:00066278

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1002/hipo.22173

UT WoS

000327157200019

Keywords in English

intracranial recordings; auditory task; hippocampus; ERP latency; motor response

Abstract

V originále

A hippocampal prominent event-related potential (ERP) with a peak latency at around 450 ms is consistently observed as a correlate of hippocampal activity during various cognitive tasks. Some intracranial EEG studies demonstrated that the amplitude of this hippocampal potential was greater in response to stimuli requiring an overt motor response, in comparison with stimuli for which no motor response is required. These findings could indicate that hippocampal evoked activity is related to movement execution as well as stimulus evaluation and associated memory processes. The aim of the present study was to investigate the temporal relationship between the hippocampal negative potential latency and motor responses. We analyzed ERPs recorded with 22 depth electrodes implanted into the hippocampi of 11 epileptic patients. Subjects were instructed to press a button after the presentation of a tone. All investigated hippocampi generated a prominent negative ERP peaking at approximately 420 ms. In 16 from 22 cases we found that the ERP latency did not correlate with the reaction time; in different subjects, this potential could either precede or follow the motor response. Our results indicate that the hippocampal negative ERP occurs independently of motor execution. We suggest that hippocampal evoked activity, recorded in a simple sensorimotor task, is related to the evaluation of stimulus meaning within the context of situation.

Links

ED1.1.00/02.0068, research and development project

Name: CEITEC - central european institute of technology

GAP103/11/0933, research and development project

Name: Analýza vysokofrekvenčního EEG signálu z hlubokých mozkových elektrod

Investor: Czech Science Foundation

MSM0021622404, plan (intention)

Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.

Citovat

ROMAN, Robert, Milan BRÁZDIL, Jan CHLÁDEK, Ivan REKTOR, Pavel JURÁK, Miroslav SVĚTLÁK, Alena DAMBORSKÁ, Daniel Joel SHAW and Miloslav KUKLETA. Hippocampal negative event-related potential recorded in humans during a simple sensorimotor task occurs independently of motor execution. Hippocampus. Hoboken, USA: WILEY-BLACKWELL, 2013, vol. 23, No 12, p. 1337-1344. ISSN 1050-9631. Available from: https://dx.doi.org/10.1002/hipo.22173.

@article{1119440,
   author = {Roman, Robert and Brázdil, Milan and Chládek, Jan and Rektor, Ivan and Jurák, Pavel and Světlák, Miroslav and Damborská, Alena and Shaw, Daniel Joel and Kukleta, Miloslav},
   article_location = {Hoboken, USA},
   article_number = {12},
   doi = {http://dx.doi.org/10.1002/hipo.22173},
   keywords = {intracranial recordings; auditory task; hippocampus; ERP latency; motor response},
   language = {eng},
   issn = {1050-9631},
   journal = {Hippocampus},
   title = {Hippocampal negative event-related potential recorded in humans during a simple sensorimotor task occurs independently of motor execution},
   url = {http://onlinelibrary.wiley.com/doi/10.1002/hipo.22173/abstract;jsessionid=4068795D783BE1A4D586B1DBC14D6066.f02t01},
   volume = {23},
   year = {2013}
}

TY  - JOUR
ID  - 1119440
AU  - Roman, Robert - Brázdil, Milan - Chládek, Jan - Rektor, Ivan - Jurák, Pavel - Světlák, Miroslav - Damborská, Alena - Shaw, Daniel Joel - Kukleta, Miloslav
PY  - 2013
TI  - Hippocampal negative event-related potential recorded in humans during a simple sensorimotor task occurs independently of motor execution
JF  - Hippocampus
VL  - 23
IS  - 12
SP  - 1337-1344
EP  - 1337-1344
PB  - WILEY-BLACKWELL
SN  - 10509631
KW  - intracranial recordings
KW  - auditory task
KW  - hippocampus
KW  - ERP latency
KW  - motor response
UR  - http://onlinelibrary.wiley.com/doi/10.1002/hipo.22173/abstract;jsessionid=4068795D783BE1A4D586B1DBC14D6066.f02t01
L2  - http://onlinelibrary.wiley.com/doi/10.1002/hipo.22173/abstract;jsessionid=4068795D783BE1A4D586B1DBC14D6066.f02t01
N2  - A hippocampal prominent event-related potential (ERP) with a peak latency at around 450 ms is consistently observed as a correlate of hippocampal activity during various cognitive tasks. Some intracranial EEG studies demonstrated that the amplitude of this hippocampal potential was greater in response to stimuli requiring an overt motor response, in comparison with stimuli for which no motor response is required. These findings could indicate that hippocampal evoked activity is related to movement execution as well as stimulus evaluation and associated memory processes. The aim of the present study was to investigate the temporal relationship between the hippocampal negative potential latency and motor responses. We analyzed ERPs recorded with 22 depth electrodes implanted into the hippocampi of 11 epileptic patients. Subjects were instructed to press a button after the presentation of a tone. All investigated hippocampi generated a prominent negative ERP peaking at approximately 420 ms. In 16 from 22 cases we found that the ERP latency did not correlate with the reaction time; in different subjects, this potential could either precede or follow the motor response. Our results indicate that the hippocampal negative ERP occurs independently of motor execution. We suggest that hippocampal evoked activity, recorded in a simple sensorimotor task, is related to the evaluation of stimulus meaning within the context of situation.
ER  -

ROMAN, Robert, Milan BRÁZDIL, Jan CHLÁDEK, Ivan REKTOR, Pavel JURÁK, Miroslav SVĚTLÁK, Alena DAMBORSKÁ, Daniel Joel SHAW and Miloslav KUKLETA. Hippocampal negative event-related potential recorded in humans during a simple sensorimotor task occurs independently of motor execution. \textit{Hippocampus}. Hoboken, USA: WILEY-BLACKWELL, 2013, vol.~23, No~12, p.~1337-1344. ISSN~1050-9631. Available from: https://dx.doi.org/10.1002/hipo.22173.

Detailed Information on Publication Record