| PILÁTOVÁ, Kateřina, Kristína GREPLOVÁ, Regina DEMLOVÁ, Beatrix BENCSIKOVÁ, Giannoula Lakka KLEMENT and Lenka ZDRAŽILOVÁ DUBSKÁ. Role of platelet chemokines, PF-4 and CTAP-III, in cancer biology. Journal of Hematology & Oncology. LONDON: BIOMED CENTRAL LTD, 2013, vol. 6, No 42, p. 1-8. ISSN 1756-8722. Available from: https://dx.doi.org/10.1186/1756-8722-6-42. |
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@article{1119471,
author = {Pilátová, Kateřina and Greplová, Kristína and Demlová, Regina and Bencsiková, Beatrix and Klement, Giannoula Lakka and Zdražilová Dubská, Lenka},
article_location = {LONDON},
article_number = {42},
doi = {http://dx.doi.org/10.1186/1756-8722-6-42},
keywords = {Platelet; PF-4; CTAP-III; Cancer; Angiogenesis; IL-8; Inflammation},
language = {eng},
issn = {1756-8722},
journal = {Journal of Hematology & Oncology},
title = {Role of platelet chemokines, PF-4 and CTAP-III, in cancer biology},
url = {http://www.jhoonline.org/content/6/1/42},
volume = {6},
year = {2013}
}
TY - JOUR
ID - 1119471
AU - Pilátová, Kateřina - Greplová, Kristína - Demlová, Regina - Bencsiková, Beatrix - Klement, Giannoula Lakka - Zdražilová Dubská, Lenka
PY - 2013
TI - Role of platelet chemokines, PF-4 and CTAP-III, in cancer biology
JF - Journal of Hematology & Oncology
VL - 6
IS - 42
SP - 1-8
EP - 1-8
PB - BIOMED CENTRAL LTD
SN - 17568722
KW - Platelet
KW - PF-4
KW - CTAP-III
KW - Cancer
KW - Angiogenesis
KW - IL-8
KW - Inflammation
UR - http://www.jhoonline.org/content/6/1/42
N2 - With the recent addition of anti-angiogenic agents to cancer treatment, the angiogenesis regulators in platelets are gaining importance. Platelet factor 4 (PF-4/CXCL4) and Connective tissue activating peptide III (CTAP-III) are two platelet-associated chemokines that modulate tumor angiogenesis, inflammation within the tumor microenvironment, and in turn tumor growth. Here, we review the role of PF-4 and CTAP-III in the regulation of tumor angiogenesis; the results of clinical trial using recombinant PF-4 (rPF-4); and the use of PF-4 and CTAP-III as cancer biomarkers.
ER -
PILÁTOVÁ, Kateřina, Kristína GREPLOVÁ, Regina DEMLOVÁ, Beatrix BENCSIKOVÁ, Giannoula Lakka KLEMENT and Lenka ZDRAŽILOVÁ DUBSKÁ. Role of platelet chemokines, PF-4 and CTAP-III, in cancer biology. \textit{Journal of Hematology \&{} Oncology}. LONDON: BIOMED CENTRAL LTD, 2013, vol.~6, No~42, p.~1-8. ISSN~1756-8722. Available from: https://dx.doi.org/10.1186/1756-8722-6-42.
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