Novel Electrochemical Biosensor for Simultaneous Detection of
Adenine and Guanine Based on Cu2O Nanoparticles

D 2012

Novel Electrochemical Biosensor for Simultaneous Detection of Adenine and Guanine Based on Cu2O Nanoparticles

CHOMOUCKA, Jana, Jan PRASEK, Petra BUSINOVA, Libuše TRNKOVÁ, Jana DRBOHLAVOVÁ et. al.

Basic information

Original name

Novel Electrochemical Biosensor for Simultaneous Detection of Adenine and Guanine Based on Cu2O Nanoparticles

Authors

CHOMOUCKA, Jana, Jan PRASEK, Petra BUSINOVA, Libuše TRNKOVÁ, Jana DRBOHLAVOVÁ, Jan PEKAREK, Radim HRDY and Jaromír HUBÁLEK

Edition

47. vyd. Amsterdam, 26th European Conference on Solid-State Transducers, EUROSENSOR 2012, p. 702-705, 4 pp. 2012

Publisher

ELSEVIER SCIENCE BV, SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS

Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

10403 Physical chemistry

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

Publication form

printed version "print"

Organization unit

Faculty of Science

ISSN

DOI

http://dx.doi.org/10.1016/j.proeng.2012.09.244

UT WoS

000312953300175

Keywords in English

Thick film technology; electrochemistry; cyclic voltametry; copper(I) oxide; purines

Abstract

V originále

In this paper Cu2O nanoparticles were prepared and used for the construction of novel electrochemical voltammetric biosensor for the simultaneous detection of adenine and guanine. Cu2O nanoparticles were synthesized via simple wet chemical route, where glucose was used as a reductant. The nanoparticles were characterized by SEM and XRD analysis, which showed the presence of spherical aggregations with diameter of 1000 nm. These nanoparticles were successfully used for fabrication of spray-coated and screen-printed working electrodes on alumina substrate for the electrochemical detection of purine bases. We observed that Cu(I) reacts with adenine to form insoluble complex that accumulates on the electrode surface and causes the decrease of current response. In the case of guanine, we did not observed any significant decrease of current response which is probably caused by adsorption of guanine on the electrode surface.

Links

MUNI/A/0992/2009, interní kód MU

Name: Vývoj metodologie a instrumentace analytické chemie pro studium složení a vlastností přírodních a syntetických materiálů (Acronym: MIA)

Investor: Masaryk University, Category A

Citovat

CHOMOUCKA, Jana, Jan PRASEK, Petra BUSINOVA, Libuše TRNKOVÁ, Jana DRBOHLAVOVÁ, Jan PEKAREK, Radim HRDY and Jaromír HUBÁLEK. Novel Electrochemical Biosensor for Simultaneous Detection of Adenine and Guanine Based on Cu2O Nanoparticles. In 26th European Conference on Solid-State Transducers, EUROSENSOR 2012. 47th ed. Amsterdam: ELSEVIER SCIENCE BV, SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, 2012, p. 702-705. ISSN 1877-7058. Available from: https://dx.doi.org/10.1016/j.proeng.2012.09.244.

@inproceedings{1119882,
   author = {Chomoucka, Jana and Prasek, Jan and Businova, Petra and Trnková, Libuše and Drbohlavová, Jana and Pekarek, Jan and Hrdy, Radim and Hubálek, Jaromír},
   address = {Amsterdam},
   booktitle = {26th European Conference on Solid-State Transducers, EUROSENSOR 2012},
   doi = {http://dx.doi.org/10.1016/j.proeng.2012.09.244},
   edition = {47},
   keywords = {Thick film technology; electrochemistry; cyclic voltametry; copper(I) oxide; purines},
   howpublished = {tištěná verze "print"},
   language = {eng},
   location = {Amsterdam},
   pages = {702-705},
   publisher = {ELSEVIER SCIENCE BV, SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS},
   title = {Novel Electrochemical Biosensor for Simultaneous Detection of Adenine and Guanine Based on Cu2O Nanoparticles},
   year = {2012}
}

TY  - JOUR
ID  - 1119882
AU  - Chomoucka, Jana - Prasek, Jan - Businova, Petra - Trnková, Libuše - Drbohlavová, Jana - Pekarek, Jan - Hrdy, Radim - Hubálek, Jaromír
PY  - 2012
TI  - Novel Electrochemical Biosensor for Simultaneous Detection of Adenine and Guanine Based on Cu2O Nanoparticles
PB  - ELSEVIER SCIENCE BV, SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
CY  - Amsterdam
KW  - Thick film technology
KW  - electrochemistry
KW  - cyclic voltametry
KW  - copper(I) oxide
KW  - purines
N2  - In this paper Cu2O nanoparticles were prepared and used for the construction of novel electrochemical voltammetric biosensor for the simultaneous detection of adenine and guanine. Cu2O nanoparticles were synthesized via simple wet chemical route, where glucose was used as a reductant. The nanoparticles were characterized by SEM and XRD analysis, which showed the presence of spherical aggregations with diameter of 1000 nm. These nanoparticles were successfully used for fabrication of spray-coated and screen-printed working electrodes on alumina substrate for the electrochemical detection of purine bases. We observed that Cu(I) reacts with adenine to form insoluble complex that accumulates on the electrode surface and causes the decrease of current response. In the case of guanine, we did not observed any significant decrease of current response which is probably caused by adsorption of guanine on the electrode surface.
ER  -

CHOMOUCKA, Jana, Jan PRASEK, Petra BUSINOVA, Libuše TRNKOVÁ, Jana DRBOHLAVOVÁ, Jan PEKAREK, Radim HRDY and Jaromír HUBÁLEK. Novel Electrochemical Biosensor for Simultaneous Detection of Adenine and Guanine Based on Cu2O Nanoparticles. In \textit{26th European Conference on Solid-State Transducers, EUROSENSOR 2012}. 47th ed. Amsterdam: ELSEVIER SCIENCE BV, SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, 2012, p.~702-705. ISSN~1877-7058. Available from: https://dx.doi.org/10.1016/j.proeng.2012.09.244.

Detailed Information on Publication Record