CHOMOUCKA, Jana, Jan PRASEK, Petra BUSINOVA, Libuše TRNKOVÁ, Jana DRBOHLAVOVÁ, Jan PEKAREK, Radim HRDY and Jaromír HUBÁLEK. Novel Electrochemical Biosensor for Simultaneous Detection of Adenine and Guanine Based on Cu2O Nanoparticles. In 26th European Conference on Solid-State Transducers, EUROSENSOR 2012. 47th ed. Amsterdam: ELSEVIER SCIENCE BV, SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, 2012, p. 702-705. ISSN 1877-7058. Available from: https://dx.doi.org/10.1016/j.proeng.2012.09.244.
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Basic information
Original name Novel Electrochemical Biosensor for Simultaneous Detection of Adenine and Guanine Based on Cu2O Nanoparticles
Authors CHOMOUCKA, Jana, Jan PRASEK, Petra BUSINOVA, Libuše TRNKOVÁ, Jana DRBOHLAVOVÁ, Jan PEKAREK, Radim HRDY and Jaromír HUBÁLEK.
Edition 47. vyd. Amsterdam, 26th European Conference on Solid-State Transducers, EUROSENSOR 2012, p. 702-705, 4 pp. 2012.
Publisher ELSEVIER SCIENCE BV, SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 10403 Physical chemistry
Country of publisher Netherlands
Confidentiality degree is not subject to a state or trade secret
Publication form printed version "print"
Organization unit Faculty of Science
ISSN 1877-7058
Doi http://dx.doi.org/10.1016/j.proeng.2012.09.244
UT WoS 000312953300175
Keywords in English Thick film technology; electrochemistry; cyclic voltametry; copper(I) oxide; purines
Tags AKR, rivok, ZR
Changed by Changed by: Ing. Andrea Mikešková, učo 137293. Changed: 29/4/2014 16:55.
Abstract
In this paper Cu2O nanoparticles were prepared and used for the construction of novel electrochemical voltammetric biosensor for the simultaneous detection of adenine and guanine. Cu2O nanoparticles were synthesized via simple wet chemical route, where glucose was used as a reductant. The nanoparticles were characterized by SEM and XRD analysis, which showed the presence of spherical aggregations with diameter of 1000 nm. These nanoparticles were successfully used for fabrication of spray-coated and screen-printed working electrodes on alumina substrate for the electrochemical detection of purine bases. We observed that Cu(I) reacts with adenine to form insoluble complex that accumulates on the electrode surface and causes the decrease of current response. In the case of guanine, we did not observed any significant decrease of current response which is probably caused by adsorption of guanine on the electrode surface.
Links
MUNI/A/0992/2009, interní kód MUName: Vývoj metodologie a instrumentace analytické chemie pro studium složení a vlastností přírodních a syntetických materiálů (Acronym: MIA)
Investor: Masaryk University, Category A
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