PRAUSOVA, J., K. KUBACKOVA, Ladislav DUŠEK, S. VINAKURAU, T. PIKUS, B. MALINOVA, J. HOCH, R. KODET and Z. LINKE. Influence of neoadjuvant treatment of rectal carcinoma on operability and incidence of distant metastases. Bratislavské lékarske listy. Bratislava: Veda, 2013, vol. 114, No 8, p. 469-473. ISSN 0006-9248. doi:10.4149/BLL_2013_098.
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Basic information
Original name Influence of neoadjuvant treatment of rectal carcinoma on operability and incidence of distant metastases
Authors PRAUSOVA, J. (203 Czech Republic), K. KUBACKOVA (203 Czech Republic), Ladislav DUŠEK (203 Czech Republic, guarantor, belonging to the institution), S. VINAKURAU (203 Czech Republic), T. PIKUS (203 Czech Republic), B. MALINOVA (203 Czech Republic), J. HOCH (203 Czech Republic), R. KODET (203 Czech Republic) and Z. LINKE (203 Czech Republic).
Edition Bratislavské lékarske listy, Bratislava, Veda, 2013, 0006-9248.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30200 3.2 Clinical medicine
Country of publisher Slovakia
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.446
RIV identification code RIV/00216224:14110/13:00069217
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.4149/BLL_2013_098
UT WoS 000330269900009
Keywords in English rectal carcinoma; naoadjuvant treatment; chemo-radiotherapy before surgery; angioinvasion
Tags International impact, Reviewed
Changed by Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 26. 4. 2014 12:38.
Abstract
In the Czech Republic, rectal carcinoma does not only represent a medical problem, but also a socio-economic one. At our department, we treated totally 266 patients with rectal carcinoma in the years 1998 through 2006. Among our patients, neoadjuvant treatment led to a reduction in size of the tumour in 37.6 %, in 50.8 % the size did not change. In T3 tumours, the reduction in size was observed in 36.7 % of the patients and did not change in 56 %; in T4 tumours, the reduction in size was observed in 60% of the patients. In 88 % of the patients who underwent the operation, no residual tumour was found, in 9 % of patients, a residual tumour was detected. In 19 % of the patients, a local recurrence of the tumour was detected. A statistically significant relationship was proved between the appearance of the metastatic disease and the presence of angioinvasion and the size of the primary tumour according to the Duke’s classification.
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