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@article{1122858,
author = {Mlčochová, Hana and Héžová, Renata and Staník, Michal and Slabý, Ondřej},
article_location = {New York},
article_number = {1},
doi = {http://dx.doi.org/10.1016/j.urolonc.2013.04.011},
keywords = {MicroRNA; Diagnosis; Biomarker; Urologic cancer; Urothelial cancer; Bladder cancer; Prostate cancer; Renal cell carcinoma},
language = {eng},
issn = {1078-1439},
journal = {UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS},
title = {Urine microRNAs as potential noninvasive biomarkers in urologic cancers?},
url = {http://www.sciencedirect.com/science/article/pii/S107814391300197X},
volume = {32},
year = {2014}
}
TY - JOUR
ID - 1122858
AU - Mlčochová, Hana - Héžová, Renata - Staník, Michal - Slabý, Ondřej
PY - 2014
TI - Urine microRNAs as potential noninvasive biomarkers in urologic cancers?
JF - UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
VL - 32
IS - 1
SP - "41.e1"-"41.e9"
EP - "41.e1"-"41.e9"
PB - ELSEVIER SCIENCE INC
SN - 10781439
KW - MicroRNA
KW - Diagnosis
KW - Biomarker
KW - Urologic cancer
KW - Urothelial cancer
KW - Bladder cancer
KW - Prostate cancer
KW - Renal cell carcinoma
UR - http://www.sciencedirect.com/science/article/pii/S107814391300197X
L2 - http://www.sciencedirect.com/science/article/pii/S107814391300197X
N2 - Micro-ribonucleic acids (miRNAs) are small noncoding RNAs that posttranscriptionally regulate gene expression. The ability of miRNAs to inhibit translation of oncogenes and tumor suppressors implies that they may be involved in carcinogenesis. Our review focuses on the potential of urinary miRNAs to serve as biomarkers of urologic cancers. We discuss in detail the recent knowledge about the origin of urinary miRNAs, their stability, quality control, and their utility as a potential new class of biomarkers in urologic cancer. Finally, we summarize the studies focusing on detection and characterization of urinary miRNAs as potential biomarkers in bladder, prostate, and kidney cancers.
ER -
MLČOCHOVÁ, Hana, Renata HÉŽOVÁ, Michal STANÍK and Ondřej SLABÝ. Urine microRNAs as potential noninvasive biomarkers in urologic cancers? \textit{UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS}. New York: ELSEVIER SCIENCE INC, vol.~32, No~1, p.~''41.e1''-''41.e9'', 9 pp. ISSN~1078-1439. doi:10.1016/j.urolonc.2013.04.011. 2014.
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