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@article{1124509,
author = {Vaškovicová, Naděžda and Druckmüllerová, Zdena and Janisch, Roman and Škorpíková, Jiřina and Mornstein, Vojtěch},
article_location = {České Budějovice},
article_number = {4},
doi = {http://dx.doi.org/10.2478/v10136-012-0042-7},
keywords = {HL-60 cells; ultrasound biophysical effect; image analysis; nuclear pore distribution; pore diameter; freeze-etching; nuclear envelope},
language = {eng},
issn = {1214-021X},
journal = {Journal of Applied Biomedicine},
title = {Effects of therapeutic ultrasound on the nuclear envelope and nuclear pore complexes},
url = {http://jab.zsf.jcu.cz//11_4/vaskovicova11_4.htm},
volume = {11},
year = {2013}
}
TY - JOUR
ID - 1124509
AU - Vaškovicová, Naděžda - Druckmüllerová, Zdena - Janisch, Roman - Škorpíková, Jiřina - Mornstein, Vojtěch
PY - 2013
TI - Effects of therapeutic ultrasound on the nuclear envelope and nuclear pore complexes
JF - Journal of Applied Biomedicine
VL - 11
IS - 4
SP - 235-242
EP - 235-242
PB - Faculty of Health and Social Care, University of South Bohemia
SN - 1214021X
KW - HL-60 cells
KW - ultrasound biophysical effect
KW - image analysis
KW - nuclear pore distribution
KW - pore diameter
KW - freeze-etching
KW - nuclear envelope
UR - http://jab.zsf.jcu.cz//11_4/vaskovicova11_4.htm
L2 - http://jab.zsf.jcu.cz//11_4/vaskovicova11_4.htm
N2 - The effects of acoustic waves on membrane structures, and any resulting consequences of this treatment on membrane subunit structures, remain poorly understood, as are the principals of related clinical effects. With a focus on morphological changes in the nuclear envelope, the current study presents detailed observations of membrane structures exposed to therapeutic ultrasound. Ultrasound treatment most commonly resulted in distinct changes in the distribution of Nuclear Pore Complexes (NPCs) and mean NPC number per unit area after 30 min of repair, as well as alterations in NPC diameters on the protoplasmic face of fractured nuclear membranes after 10 min of repair. The greatest effects of ultrasound on nuclear envelope structure and NPCs were not to appear immediately, but became evident after repair processes were initiated. Results from the current study may contribute to the general view on the biophysical effects of therapeutic ultrasound on cell morphology and, particularly, the understanding of this effect in relation to the nuclear envelope.
ER -
VAŠKOVICOVÁ, Naděžda, Zdena DRUCKMÜLLEROVÁ, Roman JANISCH, Jiřina ŠKORPÍKOVÁ a Vojtěch MORNSTEIN. Effects of therapeutic ultrasound on the nuclear envelope and nuclear pore complexes. \textit{Journal of Applied Biomedicine}. České Budějovice: Faculty of Health and Social Care, University of South Bohemia, 2013, roč.~11, č.~4, s.~235-242. ISSN~1214-021X. Dostupné z: https://dx.doi.org/10.2478/v10136-012-0042-7.
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