| LONG, Quan, Fernando A. RABANAL, Dazhe MENG, Christian D. HUBER, Ashley FARLOW, Alexander PLATZER, Qingrun ZHANG, Bjarni J. VILHJÁLMSSON, Arthur KORTE, Viktoria NIZHYNSKA, Viktor VORONIN, Pamela KORTE, Laura SEDMAN, Terezie MANDÁKOVÁ, Martin LYSÁK, Uemit SEREN, Ines HELLMANN and Magnus NORDBORG. Massive genomic variation and strong selection in Arabidopsis thaliana lines from Sweden. Nature Genetics. New York: Nature Publishing Group, 2013, vol. 45, No 8, p. 884-"U218", 8 pp. ISSN 1061-4036. Available from: https://dx.doi.org/10.1038/ng.2678. |
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@article{1126885,
author = {Long, Quan and Rabanal, Fernando A. and Meng, Dazhe and Huber, Christian D. and Farlow, Ashley and Platzer, Alexander and Zhang, Qingrun and Vilhjálmsson, Bjarni J. and Korte, Arthur and Nizhynska, Viktoria and Voronin, Viktor and Korte, Pamela and Sedman, Laura and Mandáková, Terezie and Lysák, Martin and Seren, Uemit and Hellmann, Ines and Nordborg, Magnus},
article_location = {New York},
article_number = {8},
doi = {http://dx.doi.org/10.1038/ng.2678},
keywords = {RIBOSOMAL-RNA GENES; LINKAGE DISEQUILIBRIUM; WIDE ASSOCIATION; NATURAL VARIATION; DNA; POPULATIONS; SEQUENCE; POLYMORPHISM; METHYLATION; ACCESSIONS},
language = {eng},
issn = {1061-4036},
journal = {Nature Genetics},
title = {Massive genomic variation and strong selection in Arabidopsis thaliana lines from Sweden},
url = {http://www.nature.com/ng/journal/v45/n8/full/ng.2678.html},
volume = {45},
year = {2013}
}
TY - JOUR
ID - 1126885
AU - Long, Quan - Rabanal, Fernando A. - Meng, Dazhe - Huber, Christian D. - Farlow, Ashley - Platzer, Alexander - Zhang, Qingrun - Vilhjálmsson, Bjarni J. - Korte, Arthur - Nizhynska, Viktoria - Voronin, Viktor - Korte, Pamela - Sedman, Laura - Mandáková, Terezie - Lysák, Martin - Seren, Uemit - Hellmann, Ines - Nordborg, Magnus
PY - 2013
TI - Massive genomic variation and strong selection in Arabidopsis thaliana lines from Sweden
JF - Nature Genetics
VL - 45
IS - 8
SP - 884-"U218"
EP - 884-"U218"
PB - Nature Publishing Group
SN - 10614036
KW - RIBOSOMAL-RNA GENES
KW - LINKAGE DISEQUILIBRIUM
KW - WIDE ASSOCIATION
KW - NATURAL VARIATION
KW - DNA
KW - POPULATIONS
KW - SEQUENCE
KW - POLYMORPHISM
KW - METHYLATION
KW - ACCESSIONS
UR - http://www.nature.com/ng/journal/v45/n8/full/ng.2678.html
L2 - http://www.nature.com/ng/journal/v45/n8/full/ng.2678.html
N2 - Despite advances in sequencing, the goal of obtaining a comprehensive view of genetic variation in populations is still far from reached. We sequenced 180 lines of A. thaliana from Sweden to obtain as complete a picture as possible of variation in a single region. Whereas simple polymorphisms in the unique portion of the genome are readily identified, other polymorphisms are not. The massive variation in genome size identified by flow cytometry seems largely to be due to 45S rDNA copy number variation, with lines from northern Sweden having particularly large numbers of copies. Strong selection is evident in the form of long-range linkage disequilibrium (LD), as well as in LD between nearby compensatory mutations. Many footprints of selective sweeps were found in lines from northern Sweden, and a massive global sweep was shown to have involved a 700-kb transposition.
ER -
LONG, Quan, Fernando A. RABANAL, Dazhe MENG, Christian D. HUBER, Ashley FARLOW, Alexander PLATZER, Qingrun ZHANG, Bjarni J. VILHJÁLMSSON, Arthur KORTE, Viktoria NIZHYNSKA, Viktor VORONIN, Pamela KORTE, Laura SEDMAN, Terezie MANDÁKOVÁ, Martin LYSÁK, Uemit SEREN, Ines HELLMANN and Magnus NORDBORG. Massive genomic variation and strong selection in Arabidopsis thaliana lines from Sweden. \textit{Nature Genetics}. New York: Nature Publishing Group, 2013, vol.~45, No~8, p.~884-''U218'', 8 pp. ISSN~1061-4036. Available from: https://dx.doi.org/10.1038/ng.2678.
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