Interaction of Notch and gp130 Signaling in the Maintenance of
Neural Stem and Progenitor Cells

J 2014

Interaction of Notch and gp130 Signaling in the Maintenance of Neural Stem and Progenitor Cells

KOTASOVÁ, Hana, Jiřina PROCHÁZKOVÁ and Jiří PACHERNÍK

Basic information

Original name

Interaction of Notch and gp130 Signaling in the Maintenance of Neural Stem and Progenitor Cells

Authors

KOTASOVÁ, Hana (203 Czech Republic, belonging to the institution), Jiřina PROCHÁZKOVÁ (203 Czech Republic, belonging to the institution) and Jiří PACHERNÍK (203 Czech Republic, guarantor, belonging to the institution)

Edition

Cellular and Molecular Neurobiology, NEW YORK, Springer Netherlands, 2014, 0272-4340

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10601 Cell biology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 2.506

RIV identification code

RIV/00216224:14310/14:00074806

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.1007/s10571-013-9996-6

UT WoS

000330343100001

Keywords in English

Neural stem cell; Neural progenitor; Signal transduction; Notch; gp130

Abstract

V originále

Notch and gp130 signaling are involved in the regulation of multiple cellular processes across various tissues during animal ontogenesis. In the developing nervous system, both signaling pathways intervene at many stages to determine cell fate-from the first neural lineage commitment and generation of neuronal precursors, to the terminal specification of cells as neurons and glia. In most cases, the effects of Notch and gp130 signaling in these processes are similar. The aim of the current review was to summarize the knowledge regarding the roles of Notch and gp130 signaling in the maintenance of neural stem and progenitor cells during animal ontogenesis, from early embryo to adult. Recent data show a direct crosstalk between these signaling pathways that seems to be specific for a particular type of neural progenitors.

Links

MSM0021622430, plan (intention)

Name: Funkční a molekulární charakteristiky nádorových a normálních kmenových buněk - identifikace cílů pro nová terapeutika a terapeutické strategie

Investor: Ministry of Education, Youth and Sports of the CR, Functional and molecular characteristics of cancer and normal stem cells - identification of targets for novel therapeutics and therapeutic strategies

Citovat

KOTASOVÁ, Hana, Jiřina PROCHÁZKOVÁ and Jiří PACHERNÍK. Interaction of Notch and gp130 Signaling in the Maintenance of Neural Stem and Progenitor Cells. Cellular and Molecular Neurobiology. NEW YORK: Springer Netherlands, 2014, vol. 34, No 1, p. 1-15. ISSN 0272-4340. Available from: https://dx.doi.org/10.1007/s10571-013-9996-6.

@article{1128392,
   author = {Kotasová, Hana and Procházková, Jiřina and Pacherník, Jiří},
   article_location = {NEW YORK},
   article_number = {1},
   doi = {http://dx.doi.org/10.1007/s10571-013-9996-6},
   keywords = {Neural stem cell; Neural progenitor; Signal transduction; Notch; gp130},
   language = {eng},
   issn = {0272-4340},
   journal = {Cellular and Molecular Neurobiology},
   title = {Interaction of Notch and gp130 Signaling in the Maintenance of Neural Stem and Progenitor Cells},
   url = {http://link.springer.com/article/10.1007%2Fs10571-013-9996-6},
   volume = {34},
   year = {2014}
}

TY  - JOUR
ID  - 1128392
AU  - Kotasová, Hana - Procházková, Jiřina - Pacherník, Jiří
PY  - 2014
TI  - Interaction of Notch and gp130 Signaling in the Maintenance of Neural Stem and Progenitor Cells
JF  - Cellular and Molecular Neurobiology
VL  - 34
IS  - 1
SP  - 1-15
EP  - 1-15
PB  - Springer Netherlands
SN  - 02724340
KW  - Neural stem cell
KW  - Neural progenitor
KW  - Signal transduction
KW  - Notch
KW  - gp130
UR  - http://link.springer.com/article/10.1007%2Fs10571-013-9996-6
N2  - Notch and gp130 signaling are involved in the regulation of multiple cellular processes across various tissues during animal ontogenesis. In the developing nervous system, both signaling pathways intervene at many stages to determine cell fate-from the first neural lineage commitment and generation of neuronal precursors, to the terminal specification of cells as neurons and glia. In most cases, the effects of Notch and gp130 signaling in these processes are similar. The aim of the current review was to summarize the knowledge regarding the roles of Notch and gp130 signaling in the maintenance of neural stem and progenitor cells during animal ontogenesis, from early embryo to adult. Recent data show a direct crosstalk between these signaling pathways that seems to be specific for a particular type of neural progenitors.
ER  -

KOTASOVÁ, Hana, Jiřina PROCHÁZKOVÁ and Jiří PACHERNÍK. Interaction of Notch and gp130 Signaling in the Maintenance of Neural Stem and Progenitor Cells. \textit{Cellular and Molecular Neurobiology}. NEW YORK: Springer Netherlands, 2014, vol.~34, No~1, p.~1-15. ISSN~0272-4340. Available from: https://dx.doi.org/10.1007/s10571-013-9996-6.

Detailed Information on Publication Record