SOŠKA, Vladimír, Michaela FRANTISOVÁ, Petr DOBŠÁK, Ladislav DUŠEK, Jiří JARKOVSKÝ, Marie NOVÁKOVÁ, Kohji SHIRAI, Lenka FAJKUSOVÁ and Tomáš FREIBERGER. Cardio-Ankle Vascular Index in Subjects with Dyslipidaemia and Other Cardiovascular Risk Factors. JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS. TOKYO: JAPAN ATHEROSCLEROSIS SOC, 2013, vol. 20, No 5, p. 443-451. ISSN 1340-3478. doi:10.5551/jat.15420.
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Basic information
Original name Cardio-Ankle Vascular Index in Subjects with Dyslipidaemia and Other Cardiovascular Risk Factors
Authors SOŠKA, Vladimír (203 Czech Republic, guarantor, belonging to the institution), Michaela FRANTISOVÁ (203 Czech Republic, belonging to the institution), Petr DOBŠÁK (203 Czech Republic, belonging to the institution), Ladislav DUŠEK (203 Czech Republic, belonging to the institution), Jiří JARKOVSKÝ (203 Czech Republic, belonging to the institution), Marie NOVÁKOVÁ (203 Czech Republic, belonging to the institution), Kohji SHIRAI (392 Japan), Lenka FAJKUSOVÁ (203 Czech Republic, belonging to the institution) and Tomáš FREIBERGER (203 Czech Republic, belonging to the institution).
Edition JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, TOKYO, JAPAN ATHEROSCLEROSIS SOC, 2013, 1340-3478.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30201 Cardiac and Cardiovascular systems
Country of publisher Japan
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 2.770
RIV identification code RIV/00216224:14110/13:00070319
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.5551/jat.15420
UT WoS 000328731700003
Keywords in English Dyslipidaemia; Cardio-ankle vascular index; Hypertension; Diabetes mellitus; Smoking
Tags EL OK, podil
Tags International impact, Reviewed
Changed by Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 29. 4. 2014 14:24.
Abstract
Aim: The cardio-ankle vascular index (CAVI) is a novel non-invasive marker of arterial stiffness and atherosclerosis. The aim of this work was to examine whether the CAVI value in patients with dyslipidaemia (DLP) is increased by the presence of other cardiovascular risk factors: hypertension, diabetes mellitus, and smoking. Methods: A total of 392 subjects with DLP (166 male, 226 female), with a median age of 58.5 and 5-95 percentile range 32.2-73.9 years were examined. CAVI was measured using the VaSera 1500 system. Results: CAVI correlated significantly with age (p<0.001) and both systolic (p<0.001) and diastolic (p=0.002) blood pressure; higher values were found in men (p=0.034) than in women in the 56-65 age group. There was no significant difference in CAVI between smokers and non-smokers (p=0.217) and between subjects with and without diabetes mellitus (p=0.424). CAVI was significantly higher in subjects with hypertension than in the normotensive group (p<0.001) and in statin-treated subjects than in those without statins (p<0.001); however, CAVI values adjusted for age and sex did not differ significantly between these groups. Adjusted CAVI values were higher only in smokers than in non-smokers (former smokers) (p<0.001). Conclusion: The study proves conclusively that the CAVI value in DLP patients is not significantly affected by hypertension and diabetes mellitus, but it is increased by smoking.
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