Cardio-Ankle Vascular Index in Subjects with Dyslipidaemia and
Other Cardiovascular Risk Factors

J 2013

Cardio-Ankle Vascular Index in Subjects with Dyslipidaemia and Other Cardiovascular Risk Factors

SOŠKA, Vladimír; Michaela FRANTISOVÁ; Petr DOBŠÁK; Ladislav DUŠEK; Jiří JARKOVSKÝ et. al.

Basic information

Original name

Cardio-Ankle Vascular Index in Subjects with Dyslipidaemia and Other Cardiovascular Risk Factors

Authors

SOŠKA, Vladimír (203 Czech Republic, guarantor, belonging to the institution); Michaela FRANTISOVÁ (203 Czech Republic, belonging to the institution); Petr DOBŠÁK (203 Czech Republic, belonging to the institution); Ladislav DUŠEK (203 Czech Republic, belonging to the institution); Jiří JARKOVSKÝ (203 Czech Republic, belonging to the institution); Marie NOVÁKOVÁ (203 Czech Republic, belonging to the institution); Kohji SHIRAI (392 Japan); Lenka FAJKUSOVÁ (203 Czech Republic, belonging to the institution) and Tomáš FREIBERGER (203 Czech Republic, belonging to the institution)

Edition

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, TOKYO, JAPAN ATHEROSCLEROSIS SOC, 2013, 1340-3478

Other information

Language

English

Type of outcome

Article in a journal

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

Japan

Confidentiality degree

is not subject to a state or trade secret

Impact factor

Impact factor: 2.770

RIV identification code

RIV/00216224:14110/13:00070319

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.5551/jat.15420

UT WoS

000328731700003

Keywords in English

Dyslipidaemia; Cardio-ankle vascular index; Hypertension; Diabetes mellitus; Smoking

Abstract

V originále

Aim: The cardio-ankle vascular index (CAVI) is a novel non-invasive marker of arterial stiffness and atherosclerosis. The aim of this work was to examine whether the CAVI value in patients with dyslipidaemia (DLP) is increased by the presence of other cardiovascular risk factors: hypertension, diabetes mellitus, and smoking. Methods: A total of 392 subjects with DLP (166 male, 226 female), with a median age of 58.5 and 5-95 percentile range 32.2-73.9 years were examined. CAVI was measured using the VaSera 1500 system. Results: CAVI correlated significantly with age (p<0.001) and both systolic (p<0.001) and diastolic (p=0.002) blood pressure; higher values were found in men (p=0.034) than in women in the 56-65 age group. There was no significant difference in CAVI between smokers and non-smokers (p=0.217) and between subjects with and without diabetes mellitus (p=0.424). CAVI was significantly higher in subjects with hypertension than in the normotensive group (p<0.001) and in statin-treated subjects than in those without statins (p<0.001); however, CAVI values adjusted for age and sex did not differ significantly between these groups. Adjusted CAVI values were higher only in smokers than in non-smokers (former smokers) (p<0.001). Conclusion: The study proves conclusively that the CAVI value in DLP patients is not significantly affected by hypertension and diabetes mellitus, but it is increased by smoking.

Files attached

EL_Cardio_ankle_vascular.pdf

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Cite

SOŠKA, Vladimír; Michaela FRANTISOVÁ; Petr DOBŠÁK; Ladislav DUŠEK; Jiří JARKOVSKÝ; Marie NOVÁKOVÁ; Kohji SHIRAI; Lenka FAJKUSOVÁ and Tomáš FREIBERGER. Cardio-Ankle Vascular Index in Subjects with Dyslipidaemia and Other Cardiovascular Risk Factors. JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS. TOKYO: JAPAN ATHEROSCLEROSIS SOC, 2013, vol. 20, No 5, p. 443-451. ISSN 1340-3478. Available from: https://dx.doi.org/10.5551/jat.15420.

@article{1131274,
   author = {Soška, Vladimír and Frantisová, Michaela and Dobšák, Petr and Dušek, Ladislav and Jarkovský, Jiří and Nováková, Marie and Shirai, Kohji and Fajkusová, Lenka and Freiberger, Tomáš},
   article_location = {TOKYO},
   article_number = {5},
   doi = {http://dx.doi.org/10.5551/jat.15420},
   keywords = {Dyslipidaemia; Cardio-ankle vascular index; Hypertension; Diabetes mellitus; Smoking},
   language = {eng},
   issn = {1340-3478},
   journal = {JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS},
   title = {Cardio-Ankle Vascular Index in Subjects with Dyslipidaemia and Other Cardiovascular Risk Factors},
   volume = {20},
   year = {2013}
}

TY  - JOUR
ID  - 1131274
AU  - Soška, Vladimír - Frantisová, Michaela - Dobšák, Petr - Dušek, Ladislav - Jarkovský, Jiří - Nováková, Marie - Shirai, Kohji - Fajkusová, Lenka - Freiberger, Tomáš
PY  - 2013
TI  - Cardio-Ankle Vascular Index in Subjects with Dyslipidaemia and Other Cardiovascular Risk Factors
JF  - JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS
VL  - 20
IS  - 5
SP  - 443-451
EP  - 443-451
PB  - JAPAN ATHEROSCLEROSIS SOC
SN  - 13403478
KW  - Dyslipidaemia
KW  - Cardio-ankle vascular index
KW  - Hypertension
KW  - Diabetes mellitus
KW  - Smoking
N2  - Aim: The cardio-ankle vascular index (CAVI) is a novel non-invasive marker of arterial stiffness and atherosclerosis. The aim of this work was to examine whether the CAVI value in patients with dyslipidaemia (DLP) is increased by the presence of other cardiovascular risk factors: hypertension, diabetes mellitus, and smoking. Methods: A total of 392 subjects with DLP (166 male, 226 female), with a median age of 58.5 and 5-95 percentile range 32.2-73.9 years were examined. CAVI was measured using the VaSera 1500 system. Results: CAVI correlated significantly with age (p<0.001) and both systolic (p<0.001) and diastolic (p=0.002) blood pressure; higher values were found in men (p=0.034) than in women in the 56-65 age group. There was no significant difference in CAVI between smokers and non-smokers (p=0.217) and between subjects with and without diabetes mellitus (p=0.424). CAVI was significantly higher in subjects with hypertension than in the normotensive group (p<0.001) and in statin-treated subjects than in those without statins (p<0.001); however, CAVI values adjusted for age and sex did not differ significantly between these groups. Adjusted CAVI values were higher only in smokers than in non-smokers (former smokers) (p<0.001). Conclusion: The study proves conclusively that the CAVI value in DLP patients is not significantly affected by hypertension and diabetes mellitus, but it is increased by smoking.
ER  -

SOŠKA, Vladimír; Michaela FRANTISOVÁ; Petr DOBŠÁK; Ladislav DUŠEK; Jiří JARKOVSKÝ; Marie NOVÁKOVÁ; Kohji SHIRAI; Lenka FAJKUSOVÁ and Tomáš FREIBERGER. Cardio-Ankle Vascular Index in Subjects with Dyslipidaemia and Other Cardiovascular Risk Factors. \textit{JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS}. TOKYO: JAPAN ATHEROSCLEROSIS SOC, 2013, vol.~20, No~5, p.~443-451. ISSN~1340-3478. Available from: https://dx.doi.org/10.5551/jat.15420.

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