Global expression analysis of microRNAs in paired initial and
relapsed glioblastoma

a 2013

Global expression analysis of microRNAs in paired initial and relapsed glioblastoma

ŠÁNA, Jiří, Andrej BEŠŠE, Radek LAKOMÝ, Leoš KŘEN, Zdeňka KOSAŘOVÁ et. al.

Basic information

Original name

Global expression analysis of microRNAs in paired initial and relapsed glioblastoma

Authors

ŠÁNA, Jiří, Andrej BEŠŠE, Radek LAKOMÝ, Leoš KŘEN, Zdeňka KOSAŘOVÁ, Pavel FADRUS, Pavel ŠLAMPA, Martin SMRČKA, Rostislav VYZULA and Ondřej SLABÝ

Edition

The 18th World Congress on Advances in Oncology and 16th International Symposium on Molecular Medicine, Hotel Creta Maris Resort, Greece, 2013

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

30200 3.2 Clinical medicine

Country of publisher

Greece

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.880

Organization unit

Central European Institute of Technology

ISSN

UT WoS

000324507400014

Keywords in English

glioblastoma multiforme; miRNA; relapse

Abstract

V originále

Glioblastoma multiforme (GBM) is the most commonly occurring primary brain tumour. Despite modern therapeutic approaches based on a radical resection, concomitant chemoradiotherapy with temozolomide and adjuvant chemotherapy, the median of overall survival is around 15 months from diagnosis. This infaust prognosis is mainly caused by GBM resistance to the indicated therapy. Therefore, it is very important to find new biomarkers, which will predict a clinical outcome of GBM patients who have undergone therapy with themozolomide. Recent studies show, that miRNAs could play an important role in chemo- and radioresistance of many tumours including GBM.

Links

ED1.1.00/02.0068, research and development project

Name: CEITEC - central european institute of technology

NT13514, research and development project

Name: Analýza mikroRNA v glioblastomových kmenových buňkách: predikce léčebné odpovědi a identifikace nových terapeutických cílů u pacientů s glioblastomem

Citovat

ŠÁNA, Jiří, Andrej BEŠŠE, Radek LAKOMÝ, Leoš KŘEN, Zdeňka KOSAŘOVÁ, Pavel FADRUS, Pavel ŠLAMPA, Martin SMRČKA, Rostislav VYZULA and Ondřej SLABÝ. Global expression analysis of microRNAs in paired initial and relapsed glioblastoma. In The 18th World Congress on Advances in Oncology and 16th International Symposium on Molecular Medicine, Hotel Creta Maris Resort, Greece. 2013. ISSN 1107-3756.

@proceedings{1131975,
   author = {Šána, Jiří and Bešše, Andrej and Lakomý, Radek and Křen, Leoš and Kosařová, Zdeňka and Fadrus, Pavel and Šlampa, Pavel and Smrčka, Martin and Vyzula, Rostislav and Slabý, Ondřej},
   booktitle = {The 18th World Congress on Advances in Oncology and 16th International Symposium on Molecular Medicine, Hotel Creta Maris Resort, Greece},
   keywords = {glioblastoma multiforme; miRNA; relapse},
   language = {eng},
   title = {Global expression analysis of microRNAs in paired initial and relapsed glioblastoma},
   year = {2013}
}

TY  - CONF
ID  - 1131975
AU  - Šána, Jiří - Bešše, Andrej - Lakomý, Radek - Křen, Leoš - Kosařová, Zdeňka - Fadrus, Pavel - Šlampa, Pavel - Smrčka, Martin - Vyzula, Rostislav - Slabý, Ondřej
PY  - 2013
TI  - Global expression analysis of microRNAs in paired initial and relapsed glioblastoma
KW  - glioblastoma multiforme
KW  - miRNA
KW  - relapse
N2  - Glioblastoma multiforme (GBM) is the most commonly occurring primary brain tumour. Despite modern therapeutic approaches based on a radical resection, concomitant chemoradiotherapy with temozolomide and adjuvant chemotherapy, the median of overall survival is around 15 months from diagnosis. This infaust prognosis is mainly caused by GBM resistance to the indicated therapy. Therefore, it is very important to find new biomarkers, which will predict a clinical outcome of GBM patients who have undergone therapy with themozolomide. Recent studies show, that miRNAs could play an important role in chemo- and radioresistance of many tumours including GBM.
ER  -

ŠÁNA, Jiří, Andrej BEŠŠE, Radek LAKOMÝ, Leoš KŘEN, Zdeňka KOSAŘOVÁ, Pavel FADRUS, Pavel ŠLAMPA, Martin SMRČKA, Rostislav VYZULA and Ondřej SLABÝ. Global expression analysis of microRNAs in paired initial and relapsed glioblastoma. In \textit{The 18th World Congress on Advances in Oncology and 16th International Symposium on Molecular Medicine, Hotel Creta Maris Resort, Greece}. 2013. ISSN~1107-3756.

Detailed Information on Publication Record