From the First Spectral Analysis of Blood Pressure Variability
in the World to the Present Time: Contribution of the
Department of Physiology of the Faculty of Medicine, Masaryk
University, Brno

J 2013

From the First Spectral Analysis of Blood Pressure Variability in the World to the Present Time: Contribution of the Department of Physiology of the Faculty of Medicine, Masaryk University, Brno

NOVÁKOVÁ, Zuzana

Basic information

Original name

From the First Spectral Analysis of Blood Pressure Variability in the World to the Present Time: Contribution of the Department of Physiology of the Faculty of Medicine, Masaryk University, Brno

Authors

NOVÁKOVÁ, Zuzana (203 Czech Republic, guarantor, belonging to the institution)

Edition

Physiological Research, Praha, Institute of Physiology, Academy of Sciences of the Czech Republic, 2013, 0862-8408

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30105 Physiology

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.487

RIV identification code

RIV/00216224:14110/13:00070376

Organization unit

Faculty of Medicine

UT WoS

000323510500001

Keywords in English

Finger arterial blood pressure; Blood pressure variability; Baroreflex sensitivity; Sudden cardiac death; Hypertension; Area under receiving operating curve

Abstract

V originále

The review shows the significance of blood pressure regulation studies conducted during several decades at the Department of Physiology, Faculty of Medicine, Masaryk University, Brno. Continuous non-invasive blood pressure measurement was first introduced and patented here and, with the obtained data, the first spectral analysis of blood pressure was performed. This method was used in many different physiological studies on the relationship of blood pressure regulation to circulatory parameters, breathing, and baroreflex sensitivity. The article deals with studies on risk stratification of sudden cardiac death according to decreased baroreflex sensitivity, 24-hour heart rate variability, the amount of extrasystoles and late potentials. Importance of the new method of determination of one summation risk index is described here. A summary of the new conception of the relationship between low baroreflex sensitivity and hypertension is presented. Here, not only pathological changes of the vessel wall but also increased sympathetic activity and genetic predisposition play a role. Importance of studies conducted in young adults is highlighted, as inherited BRS decrease contributes to earlier blood pressure increase in the young. This research is highly topical, since prevention of hypertension in childhood is possible. Recent studies are dedicated to blood pressure regulation in young diabetics.

Links

MUNI/A/0951/2012, interní kód MU

Name: Studium mechanismů vzniku vybraných kardiovaskulárních nemocí a poúrazových stavů (Acronym: SMEKAONUR)

Investor: Masaryk University, Category A

Citovat

NOVÁKOVÁ, Zuzana. From the First Spectral Analysis of Blood Pressure Variability in the World to the Present Time: Contribution of the Department of Physiology of the Faculty of Medicine, Masaryk University, Brno. Physiological Research. Praha: Institute of Physiology, Academy of Sciences of the Czech Republic, 2013, vol. 62, No 4, p. 341-350. ISSN 0862-8408.

@article{1131995,
   author = {Nováková, Zuzana},
   article_location = {Praha},
   article_number = {4},
   keywords = {Finger arterial blood pressure; Blood pressure variability; Baroreflex sensitivity; Sudden cardiac death; Hypertension; Area under receiving operating curve},
   language = {eng},
   issn = {0862-8408},
   journal = {Physiological Research},
   title = {From the First Spectral Analysis of Blood Pressure Variability in the World to the Present Time: Contribution of the Department of Physiology of the Faculty of Medicine, Masaryk University, Brno},
   volume = {62},
   year = {2013}
}

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AU  - Nováková, Zuzana
PY  - 2013
TI  - From the First Spectral Analysis of Blood Pressure Variability in the World to the Present Time: Contribution of the Department of Physiology of the Faculty of Medicine, Masaryk University, Brno
JF  - Physiological Research
VL  - 62
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PB  - Institute of Physiology, Academy of Sciences of the Czech Republic
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KW  - Finger arterial blood pressure
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KW  - Baroreflex sensitivity
KW  - Sudden cardiac death
KW  - Hypertension
KW  - Area under receiving operating curve
N2  - The review shows the significance of blood pressure regulation studies conducted during several decades at the Department of Physiology, Faculty of Medicine, Masaryk University, Brno. Continuous non-invasive blood pressure measurement was first introduced and patented here and, with the obtained data, the first spectral analysis of blood pressure was performed. This method was used in many different physiological studies on the relationship of blood pressure regulation to circulatory parameters, breathing, and baroreflex sensitivity. The article deals with studies on risk stratification of sudden cardiac death according to decreased baroreflex sensitivity, 24-hour heart rate variability, the amount of extrasystoles and late potentials. Importance of the new method of determination of one summation risk index is described here. A summary of the new conception of the relationship between low baroreflex sensitivity and hypertension is presented. Here, not only pathological changes of the vessel wall but also increased sympathetic activity and genetic predisposition play a role. Importance of studies conducted in young adults is highlighted, as inherited BRS decrease contributes to earlier blood pressure increase in the young. This research is highly topical, since prevention of hypertension in childhood is possible. Recent studies are dedicated to blood pressure regulation in young diabetics.
ER  -

NOVÁKOVÁ, Zuzana. From the First Spectral Analysis of Blood Pressure Variability in the World to the Present Time: Contribution of the Department of Physiology of the Faculty of Medicine, Masaryk University, Brno. \textit{Physiological Research}. Praha: Institute of Physiology, Academy of Sciences of the Czech Republic, 2013, vol.~62, No~4, p.~341-350. ISSN~0862-8408.

Detailed Information on Publication Record