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@article{1132026,
author = {Slaninová, Iva and Pěnčíková, Kristýna and Kantorová, Jana and Slanina, Jiří and Táborská, Eva},
article_location = {Dordrecht},
article_number = {1},
doi = {http://dx.doi.org/10.1007/s11101-013-9290-8},
keywords = {Apoptosis; Anti-proliferative activity; Benzophenanthridine alkaloids; cancer; sanguinarine},
language = {eng},
issn = {1568-7767},
journal = {Phytochemistry reviews},
title = {Antitumour activities of sanguinarine and related alkaloids},
volume = {13},
year = {2014}
}
TY - JOUR
ID - 1132026
AU - Slaninová, Iva - Pěnčíková, Kristýna - Kantorová, Jana - Slanina, Jiří - Táborská, Eva
PY - 2014
TI - Antitumour activities of sanguinarine and related alkaloids
JF - Phytochemistry reviews
VL - 13
IS - 1
SP - 51-68
EP - 51-68
PB - Springer
SN - 15687767
KW - Apoptosis
KW - Anti-proliferative activity
KW - Benzophenanthridine alkaloids
KW - cancer
KW - sanguinarine
N2 - Sanguinarine is a best-known member of a relatively small group of quaternary benzo[c]phenanthridine alkaloids (QBAs). QBAs are widely distributed in the family Papaveraceae and, to a limited extent, in some species of the families Fumariaceae and Rutaceae. From a medical perspective, QBAs have many important properties. In addition to antitumour activity, they display antimicrobial, antifungal and anti-inflammatory effects. They may interact with many targets, such as DNA and microtubules, and they modify the activities of a wide variety of enzymes. This review summarises the current state of knowledge about the properties of QBAs that are important for their potential use in anticancer therapy.
ER -
SLANINOVÁ, Iva, Kristýna PĚNČÍKOVÁ, Jana KANTOROVÁ, Jiří SLANINA and Eva TÁBORSKÁ. Antitumour activities of sanguinarine and related alkaloids. \textit{Phytochemistry reviews}. Dordrecht: Springer, 2014, vol.~13, No~1, p.~51-68. ISSN~1568-7767. Available from: https://dx.doi.org/10.1007/s11101-013-9290-8.
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