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@article{1132026, author = {Slaninová, Iva and Pěnčíková, Kristýna and Kantorová, Jana and Slanina, Jiří and Táborská, Eva}, article_location = {Dordrecht}, article_number = {1}, doi = {http://dx.doi.org/10.1007/s11101-013-9290-8}, keywords = {Apoptosis; Anti-proliferative activity; Benzophenanthridine alkaloids; cancer; sanguinarine}, language = {eng}, issn = {1568-7767}, journal = {Phytochemistry reviews}, title = {Antitumour activities of sanguinarine and related alkaloids}, volume = {13}, year = {2014} }
TY - JOUR ID - 1132026 AU - Slaninová, Iva - Pěnčíková, Kristýna - Kantorová, Jana - Slanina, Jiří - Táborská, Eva PY - 2014 TI - Antitumour activities of sanguinarine and related alkaloids JF - Phytochemistry reviews VL - 13 IS - 1 SP - 51-68 EP - 51-68 PB - Springer SN - 15687767 KW - Apoptosis KW - Anti-proliferative activity KW - Benzophenanthridine alkaloids KW - cancer KW - sanguinarine N2 - Sanguinarine is a best-known member of a relatively small group of quaternary benzo[c]phenanthridine alkaloids (QBAs). QBAs are widely distributed in the family Papaveraceae and, to a limited extent, in some species of the families Fumariaceae and Rutaceae. From a medical perspective, QBAs have many important properties. In addition to antitumour activity, they display antimicrobial, antifungal and anti-inflammatory effects. They may interact with many targets, such as DNA and microtubules, and they modify the activities of a wide variety of enzymes. This review summarises the current state of knowledge about the properties of QBAs that are important for their potential use in anticancer therapy. ER -
SLANINOVÁ, Iva, Kristýna PĚNČÍKOVÁ, Jana KANTOROVÁ, Jiří SLANINA and Eva TÁBORSKÁ. Antitumour activities of sanguinarine and related alkaloids. \textit{Phytochemistry reviews}. Dordrecht: Springer, 2014, vol.~13, No~1, p.~51-68. ISSN~1568-7767. Available from: https://dx.doi.org/10.1007/s11101-013-9290-8.
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