Sperm cryopreservation before testicular cancer treatment and its subsequent utilization for the treatment of infertility.

ŽÁKOVÁ, Jana, Eva LOUSOVÁ, Pavel VENTRUBA, Igor CRHA, Hana POCHOPOVÁ, Eva TESAŘOVÁ, Jaroslava VINKLÁRKOVÁ and Mohamed Ismail Abdo NUSSIR. Sperm cryopreservation before testicular cancer treatment and its subsequent utilization for the treatment of infertility. The Scientific World Journal. New York: Hindawi Publishing Corporation, 2014, vol. 2014, "575978", p. 1-5. ISSN 1537-744X. Available from: https://dx.doi.org/10.1155/2014/575978.

Basic information

• Original name: Sperm cryopreservation before testicular cancer treatment and its subsequent utilization for the treatment of infertility.
• Name in Czech: Kryokonzervace spermatu před léčbou karcinomu varlat a jeho následné použití v léčbě infertlity
• Authors: ŽÁKOVÁ, Jana (203 Czech Republic, guarantor, belonging to the institution), Eva LOUSOVÁ (203 Czech Republic), Pavel VENTRUBA (203 Czech Republic, belonging to the institution), Igor CRHA (203 Czech Republic, belonging to the institution), Hana POCHOPOVÁ (203 Czech Republic), Eva TESAŘOVÁ (203 Czech Republic, belonging to the institution), Jaroslava VINKLÁRKOVÁ (203 Czech Republic) and Mohamed Ismail Abdo NUSSIR (203 Czech Republic, belonging to the institution).
• Edition: The Scientific World Journal, New York, Hindawi Publishing Corporation, 2014, 1537-744X.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30214 Obstetrics and gynaecology
• Country of publisher: United States of America
• Confidentiality degree: is not subject to a state or trade secret
• Impact factor: Impact factor: 1.219 in 2013
• RIV identification code: RIV/00216224:14110/14:00074873
• Organization unit: Faculty of Medicine
• Doi: http://dx.doi.org/10.1155/2014/575978
• UT WoS: 000330652400001
• Keywords (in Czech): kryokonzervace spermií karcinom varlat léčba infertility
• Keywords in English: sperm cryopreservation testicular cancer infertility treatment
• Tags: EL OK
• Tags: International impact, Reviewed

Abstract

Aims. In this study we report our results with storage of cryopreserved semen intended for preservation and subsequent infertility treatment in men with testicular cancer during the last 18 years. Methods. Cryopreserved semen of 523 men with testicular cancer was collected between October 1995 and the end of December 2012. Semen of 34 men (6.5%) was used for fertilization of their partners. They underwent 57 treatment cycles with cryopreserved, fresh, and/or donor sperm. Results. A total of 557 men have decided to freeze their semen before cancer treatment. Azoospermia was diagnosed in 34 men (6.1%), and semen was cryopreserved in 532 patients. Seminoma was diagnosed in 283 men (54.1%) and nonseminomatous germ cell tumors in 240 men (45.9%). 34 patients who returned for infertility treatment underwent 46 treatment cycles with cryopreserved sperm. Totally 16 pregnancies were achieved, that is, 34.8% pregnancy rate. Conclusion. The testicular cancer survivors have a good chance of fathering a child by using sperm cryopreserved prior to the oncology treatment, even when it contains only limited number of spermatozoa.