ECG in patients with acute heart failure can predict
in-hospital and long-term mortality

J 2014

ECG in patients with acute heart failure can predict in-hospital and long-term mortality

VÁCLAVÍK, Jan, Jindřich ŠPINAR, David VINDIŠ, Jiří VÍTOVEC, Petr WIDIMSLÝ et. al.

Basic information

Original name

ECG in patients with acute heart failure can predict in-hospital and long-term mortality

Authors

VÁCLAVÍK, Jan (203 Czech Republic), Jindřich ŠPINAR (203 Czech Republic, guarantor, belonging to the institution), David VINDIŠ (203 Czech Republic), Jiří VÍTOVEC (203 Czech Republic, belonging to the institution), Petr WIDIMSLÝ (203 Czech Republic), Čestmír ČÍHALÍK (203 Czech Republic), Aleš LINHART (203 Czech Republic), Filip MÁLEK (203 Czech Republic), Miloš TÁBORSKÝ (203 Czech Republic), Ladislav DUŠEK (203 Czech Republic, belonging to the institution), Jiří JARKOVSKÝ (203 Czech Republic, belonging to the institution), Marián FEDORCO (203 Czech Republic), Marián FELŠŐCI (703 Slovakia, belonging to the institution), Roman MIKLÍK (203 Czech Republic) and Jiří PAŘENICA (203 Czech Republic, belonging to the institution)

Edition

Internal and emergency medicine, Milan, Springer-Verlag Italia, 2014, 1828-0447

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

Italy

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 2.624

RIV identification code

RIV/00216224:14110/14:00080124

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1007/s11739-012-0862-1

UT WoS

000336422300005

Keywords in English

Acute heart failure; ECG; Electrocardiography; Mortality; Prognosis

Abstract

V originále

Initial risk stratification in patients with acute heart failure (AHF) is poorly validated. Previous studies tended to evaluate the prognostic significance of only one or two selected ECG parameters. The aim of this study was to evaluate the impact of multiple ECG parameters on mortality in AHF. The Acute Heart Failure Database (AHEAD) registry collected data from 4,153 patients admitted for AHF to seven hospitals with Catheter Laboratory facilities. Clinical variables, heart rate, duration of QRS, QT and QTC intervals, type of rhythm and ST-T segment changes on admission were collected in a web-based database. 12.7 % patients died during hospitalisation, the remainder were discharged and followed for a median of 16.2 months. The most important parameters were a prolonged QRS and a junctional rhythm, which independently predict both in-hospital mortality [QRS > 100 ms, odds ratio (OR) 1.329, 95 % CI 1.052-1.680; junctional rhythm, OR 3.715, 95 % CI 1.748-7.896] and long-term mortality (QRS > 120 ms, OR 1.428, 95 % CI 1.160-1.757; junctional rhythm, OR 2.629, 95 % CI 1.538-4.496). Increased hospitalisation mortality is predicted by ST segment elevation (OR 1.771, 95 % CI 1.383-2.269) and prolonged QTC interval >475 ms (OR 1.483, 95 % CI 1.016-2.164). Presence of atrial fibrillation and bundle branch block is associated with increased unadjusted long-term mortality, but mostly reflects more advanced heart disease, and their predictive significance is attenuated in the multivariate analysis. ECG in patients admitted for acute heart failure carries significant short- and long-term prognostic information, and should be carefully evaluated.

Links

NS9880, research and development project

Name: Komplexní managment péče o pacienty as akutním srdečním selháním, jejichstřednědobá prognóza a multivariantní prognostický model

Investor: Ministry of Health of the CR

Citovat

VÁCLAVÍK, Jan, Jindřich ŠPINAR, David VINDIŠ, Jiří VÍTOVEC, Petr WIDIMSLÝ, Čestmír ČÍHALÍK, Aleš LINHART, Filip MÁLEK, Miloš TÁBORSKÝ, Ladislav DUŠEK, Jiří JARKOVSKÝ, Marián FEDORCO, Marián FELŠŐCI, Roman MIKLÍK and Jiří PAŘENICA. ECG in patients with acute heart failure can predict in-hospital and long-term mortality. Internal and emergency medicine. Milan: Springer-Verlag Italia, 2014, vol. 9, No 3, p. 283-291. ISSN 1828-0447. Available from: https://dx.doi.org/10.1007/s11739-012-0862-1.

@article{1159115,
   author = {Václavík, Jan and Špinar, Jindřich and Vindiš, David and Vítovec, Jiří and Widimslý, Petr and Číhalík, Čestmír and Linhart, Aleš and Málek, Filip and Táborský, Miloš and Dušek, Ladislav and Jarkovský, Jiří and Fedorco, Marián and Felšőci, Marián and Miklík, Roman and Pařenica, Jiří},
   article_location = {Milan},
   article_number = {3},
   doi = {http://dx.doi.org/10.1007/s11739-012-0862-1},
   keywords = {Acute heart failure; ECG; Electrocardiography; Mortality; Prognosis},
   language = {eng},
   issn = {1828-0447},
   journal = {Internal and emergency medicine},
   title = {ECG in patients with acute heart failure can predict in-hospital and long-term mortality},
   volume = {9},
   year = {2014}
}

TY  - JOUR
ID  - 1159115
AU  - Václavík, Jan - Špinar, Jindřich - Vindiš, David - Vítovec, Jiří - Widimslý, Petr - Číhalík, Čestmír - Linhart, Aleš - Málek, Filip - Táborský, Miloš - Dušek, Ladislav - Jarkovský, Jiří - Fedorco, Marián - Felšőci, Marián - Miklík, Roman - Pařenica, Jiří
PY  - 2014
TI  - ECG in patients with acute heart failure can predict in-hospital and long-term mortality
JF  - Internal and emergency medicine
VL  - 9
IS  - 3
SP  - 283-291
EP  - 283-291
PB  - Springer-Verlag Italia
SN  - 18280447
KW  - Acute heart failure
KW  - ECG
KW  - Electrocardiography
KW  - Mortality
KW  - Prognosis
N2  - Initial risk stratification in patients with acute heart failure (AHF) is poorly validated. Previous studies tended to evaluate the prognostic significance of only one or two selected ECG parameters. The aim of this study was to evaluate the impact of multiple ECG parameters on mortality in AHF. The Acute Heart Failure Database (AHEAD) registry collected data from 4,153 patients admitted for AHF to seven hospitals with Catheter Laboratory facilities. Clinical variables, heart rate, duration of QRS, QT and QTC intervals, type of rhythm and ST-T segment changes on admission were collected in a web-based database. 12.7 % patients died during hospitalisation, the remainder were discharged and followed for a median of 16.2 months. The most important parameters were a prolonged QRS and a junctional rhythm, which independently predict both in-hospital mortality [QRS > 100 ms, odds ratio (OR) 1.329, 95 % CI 1.052-1.680; junctional rhythm, OR 3.715, 95 % CI 1.748-7.896] and long-term mortality (QRS > 120 ms, OR 1.428, 95 % CI 1.160-1.757; junctional rhythm, OR 2.629, 95 % CI 1.538-4.496). Increased hospitalisation mortality is predicted by ST segment elevation (OR 1.771, 95 % CI 1.383-2.269) and prolonged QTC interval >475 ms (OR 1.483, 95 % CI 1.016-2.164). Presence of atrial fibrillation and bundle branch block is associated with increased unadjusted long-term mortality, but mostly reflects more advanced heart disease, and their predictive significance is attenuated in the multivariate analysis. ECG in patients admitted for acute heart failure carries significant short- and long-term prognostic information, and should be carefully evaluated.
ER  -

VÁCLAVÍK, Jan, Jindřich ŠPINAR, David VINDIŠ, Jiří VÍTOVEC, Petr WIDIMSLÝ, Čestmír ČÍHALÍK, Aleš LINHART, Filip MÁLEK, Miloš TÁBORSKÝ, Ladislav DUŠEK, Jiří JARKOVSKÝ, Marián FEDORCO, Marián FELŠ$\backslash$H OCI, Roman MIKLÍK and Jiří PAŘENICA. ECG in patients with acute heart failure can predict in-hospital and long-term mortality. \textit{Internal and emergency medicine}. Milan: Springer-Verlag Italia, 2014, vol.~9, No~3, p.~283-291. ISSN~1828-0447. Available from: https://dx.doi.org/10.1007/s11739-012-0862-1.

Detailed Information on Publication Record