CHRASTINA, Jan, Zdeněk NOVÁK, Marek BALÁŽ, Ivo ŘÍHA, Martina BOČKOVÁ and Ivan REKTOR. The role of brain shift, patient age, and Parkinson's disease duration in the difference between anatomical and electrophysiological targets for subthalamic stimulation. BRITISH JOURNAL OF NEUROSURGERY. LONDON: INFORMA HEALTHCARE, 2013, vol. 27, No 5, p. 676-682. ISSN 0268-8697. doi:10.3109/02688697.2013.771726.
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Basic information
Original name The role of brain shift, patient age, and Parkinson's disease duration in the difference between anatomical and electrophysiological targets for subthalamic stimulation
Authors CHRASTINA, Jan (203 Czech Republic, guarantor, belonging to the institution), Zdeněk NOVÁK (203 Czech Republic, belonging to the institution), Marek BALÁŽ (703 Slovakia, belonging to the institution), Ivo ŘÍHA (203 Czech Republic, belonging to the institution), Martina BOČKOVÁ (203 Czech Republic, belonging to the institution) and Ivan REKTOR (203 Czech Republic, belonging to the institution).
Edition BRITISH JOURNAL OF NEUROSURGERY, LONDON, INFORMA HEALTHCARE, 2013, 0268-8697.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 0.947
RIV identification code RIV/00216224:14740/13:00071027
Organization unit Central European Institute of Technology
Doi http://dx.doi.org/10.3109/02688697.2013.771726
UT WoS 000324266800022
Keywords in English brain shift; microelectrode recording; subthalamic stimulation; stereotaxy
Tags ok, podil, rivok
Tags International impact, Reviewed
Changed by Changed by: Olga Křížová, učo 56639. Changed: 25. 4. 2014 17:20.
Abstract
Introduction. Although microrecording is common in subthalamic stimulation, microelectrode monitoring prolongs surgical time and may increase the risk of haemorrhagic complications. The main reason for electrophysiological mapping is the discrepancy between the calculated anatomical and final electrophysiological targets. The aim of this paper is to describe the relationship between anatomical and electrophysiological targets defined as the best electrophysiological recordings from multiple parallel electrode tracts, explaining the target discrepancy with attention paid to the role of brain shift and patient-and disease-related factors. Materials and methods. Subthalamic electrodes were stereotactically implanted in 58 patients using microrecording by means of parallel electrodes at defined distances. The relationship between the final electrode placement to its anatomical trajectory and the relationship between the definitive electrodes implanted on the right and left sides were analysed, as was the influence of patient age, Parkinson's disease duration, and late motor complications duration. Results. Final electrode placement matched the anatomical trajectory in 53.4% of patients on the right side and 43.1% of patients on the left side. Electrode positions were symmetrical in 38.3% of patients. The analysis of left and right electrode positions does not prove a statistically significant prevalence of lateral and posterior final electrode trajectories as could be expected from lateral and posterior movements of the brain caused by brain shift, although there was some tendency for a larger percentage of lateral electrodes on the left side. Age, Parkinson's disease duration, and L-DOPA effect duration were not confirmed as responsible factors. Conclusions. The difference between anatomical trajectory and final electrode placement supports the use of functional microelectrode monitoring in subthalamic deep brain stimulation. Brain shift is not the only causative factor of the difference. The possible roles of age, Parkinson's disease duration, and late motor complications duration were also not confirmed by study results.
Links
ED1.1.00/02.0068, research and development projectName: CEITEC - central european institute of technology
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