Fluorescein Analogue Xanthene-9-Carboxylic Acid: A
Transition-Metal Free CO Releasing Molecule Activated by Green
Light

J 2013

Fluorescein Analogue Xanthene-9-Carboxylic Acid: A Transition-Metal Free CO Releasing Molecule Activated by Green Light

ANGEL P. A., Lovely, Tomáš SLANINA, Peter ŠEBEJ, Tomáš ŠOLOMEK, Petr KLÁN et. al.

Základní údaje

Originální název

Fluorescein Analogue Xanthene-9-Carboxylic Acid: A Transition-Metal Free CO Releasing Molecule Activated by Green Light

Autoři

ANGEL P. A., Lovely (356 Indie, domácí), Tomáš SLANINA (203 Česká republika, domácí), Peter ŠEBEJ (703 Slovensko, domácí), Tomáš ŠOLOMEK (703 Slovensko, domácí) a Petr KLÁN (203 Česká republika, garant, domácí)

Vydání

Organic Letters, Washington D.C., USA, American Chemical Society, 2013, 1523-7060

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10401 Organic chemistry

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 6.324

Kód RIV

RIV/00216224:14310/13:00066765

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1021/ol4021089

UT WoS

000328864800071

Klíčová slova anglicky

Photochemistry; photoremovable protecting group; carbon monoxide

Štítky

AKR, rivok

Změněno: 1. 4. 2015 22:13, prof. RNDr. Petr Klán, Ph.D.

Anotace

V originále

6-Hydroxy-3-oxo-3H-xanthene-9-carboxylic acid is introduced as the first transition-metal-free carbon monoxide releasing molecule activated by visible light (photoCORM). This water-soluble fluorescein analogue releases carbon monoxide in both water and methanol upon irradiation at 500 nm. When selectively irradiated in the presence of hemoglobin (Hb) under physiological conditions, released CO is quantitatively trapped to form carboxyhemoglobin (COHb). The reaction progress can be accurately monitored by characteristic absorption and emission properties of the reactants and products.

Návaznosti

ED0001/01/01, projekt VaV

Název: CETOCOEN

GA13-25775S, projekt VaV

Název: Vývoj viditelným světlem aktivovatelných skupin a fluorescenčních značek pro chemii a biologii

Investor: Grantová agentura ČR, Vývoj viditelným světlem aktivovatelných skupin a fluorescenčních značek pro chemii a biologii

Citovat

ANGEL P. A., Lovely, Tomáš SLANINA, Peter ŠEBEJ, Tomáš ŠOLOMEK a Petr KLÁN. Fluorescein Analogue Xanthene-9-Carboxylic Acid: A Transition-Metal Free CO Releasing Molecule Activated by Green Light. Organic Letters. Washington D.C., USA: American Chemical Society, 2013, roč. 15, č. 17, s. 4552-4555. ISSN 1523-7060. Dostupné z: https://dx.doi.org/10.1021/ol4021089.

@article{1159866,
   author = {Angel P. A., Lovely and Slanina, Tomáš and Šebej, Peter and Šolomek, Tomáš and Klán, Petr},
   article_location = {Washington D.C., USA},
   article_number = {17},
   doi = {http://dx.doi.org/10.1021/ol4021089},
   keywords = {Photochemistry; photoremovable protecting group; carbon monoxide},
   language = {eng},
   issn = {1523-7060},
   journal = {Organic Letters},
   title = {Fluorescein Analogue Xanthene-9-Carboxylic Acid: A Transition-Metal Free CO Releasing Molecule Activated by Green Light},
   url = {http://pubs.acs.org/doi/abs/10.1021/ol4021089},
   volume = {15},
   year = {2013}
}

TY  - JOUR
ID  - 1159866
AU  - Angel P. A., Lovely - Slanina, Tomáš - Šebej, Peter - Šolomek, Tomáš - Klán, Petr
PY  - 2013
TI  - Fluorescein Analogue Xanthene-9-Carboxylic Acid: A Transition-Metal Free CO Releasing Molecule Activated by Green Light
JF  - Organic Letters
VL  - 15
IS  - 17
SP  - 4552-4555
EP  - 4552-4555
PB  - American Chemical Society
SN  - 15237060
KW  - Photochemistry
KW  - photoremovable protecting group
KW  - carbon monoxide
UR  - http://pubs.acs.org/doi/abs/10.1021/ol4021089
N2  - 6-Hydroxy-3-oxo-3H-xanthene-9-carboxylic acid is introduced as the first transition-metal-free carbon monoxide releasing molecule activated by visible light (photoCORM). This water-soluble fluorescein analogue releases carbon monoxide in both water and methanol upon irradiation at 500 nm. When selectively irradiated in the presence of hemoglobin (Hb) under physiological conditions, released CO is quantitatively trapped to form carboxyhemoglobin (COHb). The reaction progress can be accurately monitored by characteristic absorption and emission properties of the reactants and products.
ER  -

ANGEL P. A., Lovely, Tomáš SLANINA, Peter ŠEBEJ, Tomáš ŠOLOMEK a Petr KLÁN. Fluorescein Analogue Xanthene-9-Carboxylic Acid: A Transition-Metal Free CO Releasing Molecule Activated by Green Light. \textit{Organic Letters}. Washington D.C., USA: American Chemical Society, 2013, roč.~15, č.~17, s.~4552-4555. ISSN~1523-7060. Dostupné z: https://dx.doi.org/10.1021/ol4021089.

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