| HOUSER, Josef, Jan KOMÁREK, Nikola KOSTLÁNOVÁ, Gianluca CIOCI, Annabelle VARROT, Sheena KERR, Martina LAHMANN, Viviane BALLOY, John FAHY, Michel CHIGNARD, Anne IMBERTY and Michaela WIMMEROVÁ. A Soluble Fucose-Specific Lectin from Aspergillus fumigatus Conidia - Structure, Specificity and Possible Role in Fungal Pathogenicity. PLOS ONE. Public Library of Science, 2013, vol. 8, No 12, p. 1-15. ISSN 1932-6203. Available from: https://dx.doi.org/10.1371/journal.pone.0083077. |
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@article{1161282,
author = {Houser, Josef and Komárek, Jan and Kostlánová, Nikola and Cioci, Gianluca and Varrot, Annabelle and Kerr, Sheena and Lahmann, Martina and Balloy, Viviane and Fahy, John and Chignard, Michel and Imberty, Anne and Wimmerová, Michaela},
article_number = {12},
doi = {http://dx.doi.org/10.1371/journal.pone.0083077},
keywords = {lectin; Aspergillus fumigatus; protein structure},
language = {eng},
issn = {1932-6203},
journal = {PLOS ONE},
title = {A Soluble Fucose-Specific Lectin from Aspergillus fumigatus Conidia - Structure, Specificity and Possible Role in Fungal Pathogenicity},
url = {http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0083077},
volume = {8},
year = {2013}
}
TY - JOUR
ID - 1161282
AU - Houser, Josef - Komárek, Jan - Kostlánová, Nikola - Cioci, Gianluca - Varrot, Annabelle - Kerr, Sheena - Lahmann, Martina - Balloy, Viviane - Fahy, John - Chignard, Michel - Imberty, Anne - Wimmerová, Michaela
PY - 2013
TI - A Soluble Fucose-Specific Lectin from Aspergillus fumigatus Conidia - Structure, Specificity and Possible Role in Fungal Pathogenicity
JF - PLOS ONE
VL - 8
IS - 12
SP - 1-15
EP - 1-15
PB - Public Library of Science
SN - 19326203
KW - lectin
KW - Aspergillus fumigatus
KW - protein structure
UR - http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0083077
L2 - http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0083077
N2 - We focused on the lectin AFL, which was prepared in recombinant form and characterized. Its binding properties were studied using hemagglutination and glycan array analysis. We determined the specificity of the lectin towards L-fucose and fucosylated oligosaccharides. AFL was crystallized and its structure was solved. The combination of affinity to human epithelial epitopes, production by conidia and pro-inflammatory activity shows that AFL might be an important virulence factor
ER -
HOUSER, Josef, Jan KOMÁREK, Nikola KOSTLÁNOVÁ, Gianluca CIOCI, Annabelle VARROT, Sheena KERR, Martina LAHMANN, Viviane BALLOY, John FAHY, Michel CHIGNARD, Anne IMBERTY and Michaela WIMMEROVÁ. A Soluble Fucose-Specific Lectin from Aspergillus fumigatus Conidia - Structure, Specificity and Possible Role in Fungal Pathogenicity. \textit{PLOS ONE}. Public Library of Science, 2013, vol.~8, No~12, p.~1-15. ISSN~1932-6203. Available from: https://dx.doi.org/10.1371/journal.pone.0083077.
|
