HOUSER, Josef, Jan KOMÁREK, Nikola KOSTLÁNOVÁ, Gianluca CIOCI, Annabelle VARROT, Sheena KERR, Martina LAHMANN, Viviane BALLOY, John FAHY, Michel CHIGNARD, Anne IMBERTY and Michaela WIMMEROVÁ. A Soluble Fucose-Specific Lectin from Aspergillus fumigatus Conidia - Structure, Specificity and Possible Role in Fungal Pathogenicity. PLOS ONE. Public Library of Science, 2013, vol. 8, No 12, p. 1-15. ISSN 1932-6203. Available from: https://dx.doi.org/10.1371/journal.pone.0083077. |
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@article{1161282, author = {Houser, Josef and Komárek, Jan and Kostlánová, Nikola and Cioci, Gianluca and Varrot, Annabelle and Kerr, Sheena and Lahmann, Martina and Balloy, Viviane and Fahy, John and Chignard, Michel and Imberty, Anne and Wimmerová, Michaela}, article_number = {12}, doi = {http://dx.doi.org/10.1371/journal.pone.0083077}, keywords = {lectin; Aspergillus fumigatus; protein structure}, language = {eng}, issn = {1932-6203}, journal = {PLOS ONE}, title = {A Soluble Fucose-Specific Lectin from Aspergillus fumigatus Conidia - Structure, Specificity and Possible Role in Fungal Pathogenicity}, url = {http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0083077}, volume = {8}, year = {2013} }
TY - JOUR ID - 1161282 AU - Houser, Josef - Komárek, Jan - Kostlánová, Nikola - Cioci, Gianluca - Varrot, Annabelle - Kerr, Sheena - Lahmann, Martina - Balloy, Viviane - Fahy, John - Chignard, Michel - Imberty, Anne - Wimmerová, Michaela PY - 2013 TI - A Soluble Fucose-Specific Lectin from Aspergillus fumigatus Conidia - Structure, Specificity and Possible Role in Fungal Pathogenicity JF - PLOS ONE VL - 8 IS - 12 SP - 1-15 EP - 1-15 PB - Public Library of Science SN - 19326203 KW - lectin KW - Aspergillus fumigatus KW - protein structure UR - http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0083077 L2 - http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0083077 N2 - We focused on the lectin AFL, which was prepared in recombinant form and characterized. Its binding properties were studied using hemagglutination and glycan array analysis. We determined the specificity of the lectin towards L-fucose and fucosylated oligosaccharides. AFL was crystallized and its structure was solved. The combination of affinity to human epithelial epitopes, production by conidia and pro-inflammatory activity shows that AFL might be an important virulence factor ER -
HOUSER, Josef, Jan KOMÁREK, Nikola KOSTLÁNOVÁ, Gianluca CIOCI, Annabelle VARROT, Sheena KERR, Martina LAHMANN, Viviane BALLOY, John FAHY, Michel CHIGNARD, Anne IMBERTY and Michaela WIMMEROVÁ. A Soluble Fucose-Specific Lectin from Aspergillus fumigatus Conidia - Structure, Specificity and Possible Role in Fungal Pathogenicity. \textit{PLOS ONE}. Public Library of Science, 2013, vol.~8, No~12, p.~1-15. ISSN~1932-6203. Available from: https://dx.doi.org/10.1371/journal.pone.0083077.
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