| KUBA, Robert, Zdeněk NOVÁK, Jan CHRASTINA, Marta PAŽOURKOVÁ, Markéta HERMANOVÁ, Hana OŠLEJŠKOVÁ, Ivan REKTOR and Milan BRÁZDIL. Comparing the effects of cortical resection and vagus nerve stimulation in patients with nonlesional extratemporal epilepsy. EPILEPSY & BEHAVIOR. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE, 2013, vol. 28, No 3, p. 474-480. ISSN 1525-5050. Available from: https://dx.doi.org/10.1016/j.yebeh.2013.05.036. |
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@article{1164671,
author = {Kuba, Robert and Novák, Zdeněk and Chrastina, Jan and Pažourková, Marta and Hermanová, Markéta and Ošlejšková, Hana and Rektor, Ivan and Brázdil, Milan},
article_location = {SAN DIEGO},
article_number = {3},
doi = {http://dx.doi.org/10.1016/j.yebeh.2013.05.036},
keywords = {Vagus nerve stimulation; Nonlesional extratemporal epilepsy; Cortical resection; Epilepsy surgery; Cost analysis},
language = {eng},
issn = {1525-5050},
journal = {EPILEPSY & BEHAVIOR},
title = {Comparing the effects of cortical resection and vagus nerve stimulation in patients with nonlesional extratemporal epilepsy},
volume = {28},
year = {2013}
}
TY - JOUR
ID - 1164671
AU - Kuba, Robert - Novák, Zdeněk - Chrastina, Jan - Pažourková, Marta - Hermanová, Markéta - Ošlejšková, Hana - Rektor, Ivan - Brázdil, Milan
PY - 2013
TI - Comparing the effects of cortical resection and vagus nerve stimulation in patients with nonlesional extratemporal epilepsy
JF - EPILEPSY & BEHAVIOR
VL - 28
IS - 3
SP - 474-480
EP - 474-480
PB - ACADEMIC PRESS INC ELSEVIER SCIENCE
SN - 15255050
KW - Vagus nerve stimulation
KW - Nonlesional extratemporal epilepsy
KW - Cortical resection
KW - Epilepsy surgery
KW - Cost analysis
N2 - The main purpose of this retrospective study was to compare the effects of resective surgery (RESgr-26 patients) and vagus nerve stimulation (VNSgr-35 patients) on seizure frequency (2 and 5 years after surgery) in patients with nonlesional extratemporal epilepsy (NLexTLE). We analyzed hospital admission costs directly associated with epilepsy (HACE) in both groups at the same follow-up. The decrease in seizure frequency from the preoperative levels, in both VNSgr and RESgr, was statistically significant (p < 0.001). The seizure frequency reduction did not differ significantly between the follow-up visits for either group (p = 0.221 at 2 years and 0.218 at 5 years). A significantly higher number of Engel I and Engel I + II patients were found in RESgr than in VNSgr at both follow-up visits (p = 0.04 and 0.007, respectively). Using McHugh classification, we did not find statistically significant differences between both groups at both follow-up visits. Hospital admission costs directly associated with epilepsy/patient/year in both RESgr and VNSgr dropped significantly at 2- and 5-year follow-up visit and this reduction was not statistically different between RESgr and VNSgr (p = 0.232).
ER -
KUBA, Robert, Zdeněk NOVÁK, Jan CHRASTINA, Marta PAŽOURKOVÁ, Markéta HERMANOVÁ, Hana OŠLEJŠKOVÁ, Ivan REKTOR and Milan BRÁZDIL. Comparing the effects of cortical resection and vagus nerve stimulation in patients with nonlesional extratemporal epilepsy. \textit{EPILEPSY \&{}amp; BEHAVIOR}. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE, 2013, vol.~28, No~3, p.~474-480. ISSN~1525-5050. Available from: https://dx.doi.org/10.1016/j.yebeh.2013.05.036.
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