a 2013

Cell motility in early emerging apicomplexans with emphasis on gregarines and protococcidia

VALIGUROVÁ, Andrea and Andrei DIAKIN

Basic information

Original name

Cell motility in early emerging apicomplexans with emphasis on gregarines and protococcidia

Authors

VALIGUROVÁ, Andrea (703 Slovakia, guarantor, belonging to the institution) and Andrei DIAKIN (643 Russian Federation, belonging to the institution)

Edition

ICOP XIV International Congress of Protistology, 2013

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

10600 1.6 Biological sciences

Country of publisher

Canada

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14310/13:00066892

Organization unit

Faculty of Science

Keywords in English

cell motility gregarine protococcidian

Tags

International impact, Reviewed

Abstract

V originále

Apicomplexa represent one of the most successful and diverse group of unicellular parasites exhibiting unique adaptations to their life style. Their motile invasive zoites use a unique conserved form of actin-based gliding motility. Since cytoskeletal elements play an important role in various life processes of Apicomplexa, they represent a potential target for chemotherapeutic intervention. Our intent is to investigate whether the glideosome concept, proposed in Toxoplasma, could be applied also to basal apicomplexan lineages. We focus on deep-branching groups, especially gregarines and protococcidians, restricted to invertebrates. These parasites exhibit diverse modes of locomotion depending on their cell architecture and surrounding environment, e.g. slow peristalsis-like movements observed in urosporidians and protococcidia, gliding in eugregarines equipped with well-developed epicytic folds, and finally active bending, rolling or coiling known from marine archigregarines that probably evolved from hypertrophic zoite and thus retained subpellicular microtubules. Financial support provided by Czech Science Foundation No. P505/12/G112 (ECIP).

Links

GBP505/12/G112, research and development project
Name: ECIP - Evropské centrum ichtyoparazitologie
Investor: Czech Science Foundation