| DVOŘÁKOVÁ, Hana, Martin KAŠNÝ, Lucie JEDLIČKOVÁ, Karolína SKIPALOVÁ, Jana ILGOVÁ, Ewa DZIKA, Božena KOUBKOVÁ, Milan GELNAR and Libor MIKEŠ. Bioactive molecules of the blood-feeding monogenean Eudiplozoon nipponicum. In 47th Annual Meeting of the Austrian Society of Tropical Medicine, Parasitology and Migration Medicine. 2013. |
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@proceedings{1165324,
author = {Dvořáková, Hana and Kašný, Martin and Jedličková, Lucie and Skipalová, Karolína and Ilgová, Jana and Dzika, Ewa and Koubková, Božena and Gelnar, Milan and Mikeš, Libor},
booktitle = {47th Annual Meeting of the Austrian Society of Tropical Medicine, Parasitology and Migration Medicine},
keywords = {Eudiplozoon nipponicum; host-parasite interaction; blood digestion; peptidases; inhibitors; molecules; transcriptome},
language = {eng},
title = {Bioactive molecules of the blood-feeding monogenean Eudiplozoon nipponicum},
year = {2013}
}
TY - CONF
ID - 1165324
AU - Dvořáková, Hana - Kašný, Martin - Jedličková, Lucie - Skipalová, Karolína - Ilgová, Jana - Dzika, Ewa - Koubková, Božena - Gelnar, Milan - Mikeš, Libor
PY - 2013
TI - Bioactive molecules of the blood-feeding monogenean Eudiplozoon nipponicum
KW - Eudiplozoon nipponicum
KW - host-parasite interaction
KW - blood digestion
KW - peptidases
KW - inhibitors
KW - molecules
KW - transcriptome
N2 - Monogeneans of the family Diplozoidae are ectoparasitic blood-feeders inhabiting the gills of cyprinid fish. They can be significantly virulent to their hosts, causing mechanical damage to gill filaments accompanied by a risk of secondary bacterial and mycotic infections or anemia. In contrast to other blood-feeding parasites, the host-parasite "communication" at the molecular level is among monogeneans largely unknown. We performed the first insights into molecular biology of diplozoid parasites by exploring the transcriptome of the adult stage of Eudiplozoon nipponicum (group Heteronchoinea), using 454 sequencing technology (GS FLX System, ROCHE). We are primarily focused on identification and characterization of selected molecules involved in host-parasite interaction. Special attention is paid to molecules participating on digestion of host's blood (e.g. proteolytic enzymes - peptidases) and other molecules (e.g. anticoagulants) playing essential role in biological processes in the parasite.
ER -
DVOŘÁKOVÁ, Hana, Martin KAŠNÝ, Lucie JEDLIČKOVÁ, Karolína SKIPALOVÁ, Jana ILGOVÁ, Ewa DZIKA, Božena KOUBKOVÁ, Milan GELNAR and Libor MIKEŠ. Bioactive molecules of the blood-feeding monogenean Eudiplozoon nipponicum. In \textit{47th Annual Meeting of the Austrian Society of Tropical Medicine, Parasitology and Migration Medicine}. 2013.
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