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@article{1166857,
author = {Denev, Petko and Kratchanova, Maria and Číž, Milan and Lojek, Antonín and Vašíček, Ondřej and Nedelcheva, Plamena and Blazheva, Denitsa and Toshkova, Reneta and Gardeva, Elena and Yossifova, Liliya and Hyršl, Pavel and Vojtek, Libor},
article_location = {Kidlington},
article_number = {August},
doi = {http://dx.doi.org/10.1016/j.foodchem.2014.02.022},
keywords = {small fruits; polyphenols; antioxidant activity; oxidative burst; antimicrobial properties; mitogenic activity},
language = {eng},
issn = {0308-8146},
journal = {Food Chemistry},
title = {Biological activities of selected polyphenol-1 rich fruits related to immunity and gastrointestinal health},
url = {https://www.sciencedirect.com/science/article/pii/S0308814614001964},
volume = {157},
year = {2014}
}
TY - JOUR
ID - 1166857
AU - Denev, Petko - Kratchanova, Maria - Číž, Milan - Lojek, Antonín - Vašíček, Ondřej - Nedelcheva, Plamena - Blazheva, Denitsa - Toshkova, Reneta - Gardeva, Elena - Yossifova, Liliya - Hyršl, Pavel - Vojtek, Libor
PY - 2014
TI - Biological activities of selected polyphenol-1 rich fruits related to immunity and gastrointestinal health
JF - Food Chemistry
VL - 157
IS - August
SP - 37-44
EP - 37-44
PB - Elsevier Sci Ltd
SN - 03088146
KW - small fruits
KW - polyphenols
KW - antioxidant activity
KW - oxidative burst
KW - antimicrobial properties
KW - mitogenic activity
UR - https://www.sciencedirect.com/science/article/pii/S0308814614001964
L2 - https://www.sciencedirect.com/science/article/pii/S0308814614001964
N2 - Small fruits are a rich source of bioactive substances, including polyphenols, and are therefore suitable raw materials for the production of functional foods. In the current work, we studied the antioxidative properties of six fruits: rosehip, chokeberry, hawthorn, blackcurrant, blueberry and rowanberry via different methods (ORAC, TRAP, HORAC and inhibition of lipid peroxidation). Their effect on the production of reactive oxygen species (ROS) by phagocytes, antimicrobial properties against 11 human pathogens, and mitogenic effect on hamster spleen lymphocytes were also tested. Rosehip extract showed the highest antioxidant activity via ORAC, TRAP and HORAC assays, whereas blueberry extract was the most potent inhibitor of lipid peroxidation. All extracts inhibited ROS production of opsonized zymosan-activated phagocytes, indicating that extracts interfere with the signaling cascade of phagocyte activation upstream to the protein kinase C activation. Chokeberry, blackcurrant and rowanberry extracts revealed strong antimicrobial properties against a broad spectrum of microorganisms and also had the highest mitogenic activity.
ER -
DENEV, Petko, Maria KRATCHANOVA, Milan ČÍŽ, Antonín LOJEK, Ondřej VAŠÍČEK, Plamena NEDELCHEVA, Denitsa BLAZHEVA, Reneta TOSHKOVA, Elena GARDEVA, Liliya YOSSIFOVA, Pavel HYRŠL and Libor VOJTEK. Biological activities of selected polyphenol-1 rich fruits related to immunity and gastrointestinal health. \textit{Food Chemistry}. Kidlington: Elsevier Sci Ltd, 2014, vol.~157, August, p.~37-44. ISSN~0308-8146. Available from: https://dx.doi.org/10.1016/j.foodchem.2014.02.022.
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