Tissue visualization mediated by nanoparticles: from tissue staining to mass spectrometry tissue profiling and imaging

KOLÁŘOVÁ, Lenka, Petr VAŇHARA, Eladia Maria PEŇA MENDÉZ, Aleš HAMPL and Josef HAVEL. Tissue visualization mediated by nanoparticles: from tissue staining to mass spectrometry tissue profiling and imaging. Online. In Alexander Seifalian, Achala de Mel, Deepak M. Kalaskar. Nanomedicine. 1st. Manchester (UK): One Central Press (OCP), 2014, p. 467-488. ISBN 978-1-910086-01-8.

Basic information

• Original name: Tissue visualization mediated by nanoparticles: from tissue staining to mass spectrometry tissue profiling and imaging
• Authors: KOLÁŘOVÁ, Lenka (203 Czech Republic, belonging to the institution), Petr VAŇHARA (203 Czech Republic, belonging to the institution), Eladia Maria PEŇA MENDÉZ (724 Spain), Aleš HAMPL (203 Czech Republic, belonging to the institution) and Josef HAVEL (203 Czech Republic, guarantor, belonging to the institution).
• Edition: 1st. Manchester (UK), Nanomedicine, p. 467-488, 22 pp. 2014.
• Publisher: One Central Press (OCP)

Other information

• Original language: English
• Type of outcome: Chapter(s) of a specialized book
• Field of Study: 10406 Analytical chemistry
• Country of publisher: United Kingdom of Great Britain and Northern Ireland
• Confidentiality degree: is not subject to a state or trade secret
• Publication form: electronic version available online
• RIV identification code: RIV/00216224:14310/14:00073532
• Organization unit: Faculty of Science
• ISBN: 978-1-910086-01-8
• Keywords in English: Histology; Staining; Tissue imaging; Mass spectrometry; Nanomedicine; Nanoparticles
• Tags: AKR, EL OK, podil

Abstract

An extensive progress in nanotechnology led to development of variety of nanoparticles capable of specific interactions with biological structures even in living organisms. Structure and chemical properties of nanoparticles can be tailored to fit desired tasks, ranging from drug delivery to cell tracking or histopathological studies. Classical histological staining techniques of tissue sections can be complemented by information brought by specific deposition of nanoparticles in tissues and their direct visualization. Moreover, nanoparticles can enhance outputs of bioanalytical techniques, such as mass spectrometry, providing an insight to the tissue composition in a topological context. Nanoparticles applied in tissue visualization therefore contribute to composing of a complex image that broadens frontiers of current diagnostics and tissue-oriented research.

Links

• ED2.1.00/03.0086, research and development project: Name: Regionální VaV centrum pro nízkonákladové plazmové a nanotechnologické povrchové úpravy
• GA202/07/1669, research and development project: Name: Depozice termomechanicky stabilních nanostrukturovaných diamantu-podobných tenkých vrstev ve dvojfrekvenčních kapacitních výbojích

Investor: Czech Science Foundation, Deposition of thermomehanically stable nanostructured diamond-like thin films in dual frequency capacitive discharges

• MSM0021622411, plan (intention): Name: Studium a aplikace plazmochemických reakcí v neizotermickém nízkoteplotním plazmatu a jeho interakcí s povrchem pevných látek

Investor: Ministry of Education, Youth and Sports of the CR, Study and application of plasma chemical reactions in non-isothermic low temperature plasma and its interaction with solid surface

• MSM0021622430, plan (intention): Name: Funkční a molekulární charakteristiky nádorových a normálních kmenových buněk - identifikace cílů pro nová terapeutika a terapeutické strategie

Investor: Ministry of Education, Youth and Sports of the CR, Functional and molecular characteristics of cancer and normal stem cells - identification of targets for novel therapeutics and therapeutic strategies

• MUNI/M/0041/2013, interní kód MU: Name: Bioanalytical Cell and Tissue Authentication using Physical Chemistry Methods and Artificial Intelligence

Investor: Masaryk University, INTERDISCIPLINARY - Interdisciplinary research projects