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@article{1173750,
author = {Uher, Tomas and Bob, Petr},
article_location = {London},
article_number = {3},
doi = {http://dx.doi.org/10.3109/00207454.2012.746335},
keywords = {C-reactive protein; depressive symptoms; neuropathic pain; sciatica pain},
language = {eng},
issn = {0020-7454},
journal = {International Journal of Neuroscience},
title = {Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients},
volume = {123},
year = {2013}
}
TY - JOUR
ID - 1173750
AU - Uher, Tomas - Bob, Petr
PY - 2013
TI - Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients
JF - International Journal of Neuroscience
VL - 123
IS - 3
SP - 204-208
EP - 204-208
PB - Informa Healthcare
SN - 00207454
KW - C-reactive protein
KW - depressive symptoms
KW - neuropathic pain
KW - sciatica pain
N2 - There is evidence that neuropathic pain component in low back pain (LBP) patients is associated with higher ratings of comorbidities such as depression and anxiety disorders. In line with current findings, the purpose of this clinical study is to examine a hypothesis regarding a relationship of neuropathic pain component, depression, and other psychopathological symptoms in a specific group of LBP patients with sciatica pain. With respect to findings that depression is related to inflammatory changes, and inflammatory mediators may play a role in neuropathic pain generation, we have assessed also serum C-reactive protein (CRP). Results of the present study show that increased neuropathic pain component in sciatica patients is associated with elevated levels of depression, anxiety, alexithymia, and serum CRP levels. In conclusion, results of this study indicate that CRP levels in sciatica patients are closely associated with neuropathic pain.
ER -
UHER, Tomas and Petr BOB. Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients. \textit{International Journal of Neuroscience}. London: Informa Healthcare, 2013, vol.~123, No~3, p.~204-208. ISSN~0020-7454. Available from: https://dx.doi.org/10.3109/00207454.2012.746335.
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