Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein
in Sciatica Patients

J 2013

Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients

UHER, Tomas and Petr BOB

Basic information

Original name

Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients

Authors

UHER, Tomas (203 Czech Republic) and Petr BOB (203 Czech Republic, guarantor, belonging to the institution)

Edition

International Journal of Neuroscience, London, Informa Healthcare, 2013, 0020-7454

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.528

RIV identification code

RIV/00216224:14740/13:00072798

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.3109/00207454.2012.746335

UT WoS

000314898000009

Keywords in English

C-reactive protein; depressive symptoms; neuropathic pain; sciatica pain

Abstract

V originále

There is evidence that neuropathic pain component in low back pain (LBP) patients is associated with higher ratings of comorbidities such as depression and anxiety disorders. In line with current findings, the purpose of this clinical study is to examine a hypothesis regarding a relationship of neuropathic pain component, depression, and other psychopathological symptoms in a specific group of LBP patients with sciatica pain. With respect to findings that depression is related to inflammatory changes, and inflammatory mediators may play a role in neuropathic pain generation, we have assessed also serum C-reactive protein (CRP). Results of the present study show that increased neuropathic pain component in sciatica patients is associated with elevated levels of depression, anxiety, alexithymia, and serum CRP levels. In conclusion, results of this study indicate that CRP levels in sciatica patients are closely associated with neuropathic pain.

Links

ED1.1.00/02.0068, research and development project

Name: CEITEC - central european institute of technology

Citovat

UHER, Tomas and Petr BOB. Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients. International Journal of Neuroscience. London: Informa Healthcare, 2013, vol. 123, No 3, p. 204-208. ISSN 0020-7454. Available from: https://dx.doi.org/10.3109/00207454.2012.746335.

@article{1173750,
   author = {Uher, Tomas and Bob, Petr},
   article_location = {London},
   article_number = {3},
   doi = {http://dx.doi.org/10.3109/00207454.2012.746335},
   keywords = {C-reactive protein; depressive symptoms; neuropathic pain; sciatica pain},
   language = {eng},
   issn = {0020-7454},
   journal = {International Journal of Neuroscience},
   title = {Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients},
   volume = {123},
   year = {2013}
}

TY  - JOUR
ID  - 1173750
AU  - Uher, Tomas - Bob, Petr
PY  - 2013
TI  - Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients
JF  - International Journal of Neuroscience
VL  - 123
IS  - 3
SP  - 204-208
EP  - 204-208
PB  - Informa Healthcare
SN  - 00207454
KW  - C-reactive protein
KW  - depressive symptoms
KW  - neuropathic pain
KW  - sciatica pain
N2  - There is evidence that neuropathic pain component in low back pain (LBP) patients is associated with higher ratings of comorbidities such as depression and anxiety disorders. In line with current findings, the purpose of this clinical study is to examine a hypothesis regarding a relationship of neuropathic pain component, depression, and other psychopathological symptoms in a specific group of LBP patients with sciatica pain. With respect to findings that depression is related to inflammatory changes, and inflammatory mediators may play a role in neuropathic pain generation, we have assessed also serum C-reactive protein (CRP). Results of the present study show that increased neuropathic pain component in sciatica patients is associated with elevated levels of depression, anxiety, alexithymia, and serum CRP levels. In conclusion, results of this study indicate that CRP levels in sciatica patients are closely associated with neuropathic pain.
ER  -

UHER, Tomas and Petr BOB. Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients. \textit{International Journal of Neuroscience}. London: Informa Healthcare, 2013, vol.~123, No~3, p.~204-208. ISSN~0020-7454. Available from: https://dx.doi.org/10.3109/00207454.2012.746335.

Detailed Information on Publication Record