PŘIKRYL, Radovan, Libor USTOHAL, Hana PŘIKRYLOVÁ KUČEROVÁ, Tomáš KAŠPÁREK, Jiří JARKOVSKÝ, Veronika HUBLOVÁ, Michaela MAYEROVÁ a Eva ČEŠKOVÁ. Repetitive transcranial magnetic stimulation reduces cigarette consumption in schizophrenia patients. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD, roč. 49, March, s. 30-35. ISSN 0278-5846. doi:10.1016/j.pnpbp.2013.10.019. 2014.
Další formáty:   BibTeX LaTeX RIS
Základní údaje
Originální název Repetitive transcranial magnetic stimulation reduces cigarette consumption in schizophrenia patients
Autoři PŘIKRYL, Radovan (203 Česká republika, garant, domácí), Libor USTOHAL (203 Česká republika, domácí), Hana PŘIKRYLOVÁ KUČEROVÁ (203 Česká republika, domácí), Tomáš KAŠPÁREK (203 Česká republika, domácí), Jiří JARKOVSKÝ (203 Česká republika, domácí), Veronika HUBLOVÁ (203 Česká republika, domácí), Michaela MAYEROVÁ (203 Česká republika, domácí) a Eva ČEŠKOVÁ (203 Česká republika, domácí).
Vydání PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, OXFORD, PERGAMON-ELSEVIER SCIENCE LTD, 2014, 0278-5846.
Další údaje
Originální jazyk angličtina
Typ výsledku Článek v odborném periodiku
Obor 30000 3. Medical and Health Sciences
Stát vydavatele Velká Británie a Severní Irsko
Utajení není předmětem státního či obchodního tajemství
WWW URL
Impakt faktor Impact factor: 3.689
Kód RIV RIV/00216224:14740/14:00075284
Organizační jednotka Středoevropský technologický institut
Doi http://dx.doi.org/10.1016/j.pnpbp.2013.10.019
UT WoS 000329060300005
Klíčová slova anglicky Consumption; Dorsolateral prefrontal cortex; Schizophrenia; Smoking; Stimulation
Štítky EL OK, kontrola MP, ok, podil, rivok
Příznaky Mezinárodní význam, Recenzováno
Změnil Změnila: Martina Prášilová, učo 342282. Změněno: 6. 3. 2015 07:33.
Anotace
Introduction: High-frequency repetitive transcranial magnetic stimulation (rTMS) over the left dorsolateral prefrontal cortex (DLPFC) seemed to decrease tobacco consumption and craving in nicotine-dependent people without psychiatric disorder or otherwise healthy people. Even if the prevalence of cigarette smoking in schizophrenia patients is high and estimated to be between 45% and 88%, this technique has not been systematically studied in this indication in schizophrenia yet. The aim of the study: The aim of this study was to test the ability of high-frequency (10 Hz) rTMS over the left DLPFC to decrease cigarette consumption in schizophrenia patients. Methods: The study included 35 male schizophrenia patients on stable antipsychotic medication. The patients were divided into two groups: the first (18 patients) were actively stimulated and the second (17 patients) underwent sham (placebo) stimulation. The sham rTMS was administered using a purpose-built sham coil that was identical in appearance to the real coil and made the same noise but did not deliver a substantial stimulus. The rTMS was administered at the stimulation parameters: location (left dorsolateral prefrontal cortex: DLPFC), intensity of magnetic stimulation in % of motor threshold (110%), stimulation frequency (10 Hz), number of trains (20), single train duration (10 s), inter-train interval (30 s), and total number of stimulation sessions (21). In each stimulation session, 2000 TMS pulses were given, with a total of 42,000 pulses per treatment course. Patients noted the number of cigarettes smoked in the 7 days before treatment, during the whole stimulation treatment (21 days), and again for a 7-day period after treatment. Results: Cigarette consumption was statistically significantly lower in the actively stimulated patients than in the sham rTMS group as early as the first week of stimulation. No statistically relevant correlations were found in the changes of ongoing negative or depressive schizophrenia symptoms and the number of cigarettes smoked. Conclusion: High-frequency rTMS over the left DLPFC has the ability to decrease the number of cigarettes smoked in schizophrenia patients. (C) 2013 Elsevier Inc. All rights reserved.
Návaznosti
ED1.1.00/02.0068, projekt VaVNázev: CEITEC - central european institute of technology
VytisknoutZobrazeno: 29. 3. 2024 12:25