J 2014

Voltammetric Study of dsDNA Modified by Multi-redox LabelBased on N-methyl-4-hydrazino-7-nitrobenzofurazan

DAŇHEL, Aleš, Veronika RAINDLOVA, Luděk HAVRAN, Jiří BAREK, Michal HOCEK et. al.

Basic information

Original name

Voltammetric Study of dsDNA Modified by Multi-redox LabelBased on N-methyl-4-hydrazino-7-nitrobenzofurazan

Authors

DAŇHEL, Aleš (203 Czech Republic), Veronika RAINDLOVA (203 Czech Republic), Luděk HAVRAN (203 Czech Republic), Jiří BAREK (203 Czech Republic), Michal HOCEK (203 Czech Republic) and Miroslav FOJTA (203 Czech Republic, guarantor, belonging to the institution)

Edition

Electrochimica Acta, Oxford, Elsevier, 2014, 0013-4686

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10405 Electrochemistry

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 4.504

RIV identification code

RIV/00216224:14740/14:00073590

Organization unit

Central European Institute of Technology

UT WoS

000336466100045

Keywords in English

DNA; Redox labeling; N-methyl-4-hydrazino-7-nitrobenzofurazan; Silver solid amalgam electrode; Voltammetry

Tags

International impact, Reviewed
Změněno: 11/3/2015 08:36, Martina Prášilová

Abstract

V originále

Voltammetric behaviour of novel synthetic multi-redox DNA label N-methyl-4-hydrazino-7-nitrobenzofurazan (NBF), a deoxycytidine monophosphate conjugate with NBF via formylthiophenelinker (dCNBFMP), and NBF labeled model short double stranded DNA (dsDNA-NBF) were systematicallystudied at mercury meniscus modified silver solid amalgam electrode (m-AgSAE) for the first time inthis work. Used modification resulted in increase of selectivity andsensitivity of the DNA voltammetric determination.

Links

GBP206/12/G151, research and development project
Name: Centrum nových přístupů k bioanalýze a molekulární diagnostice