Detailed Information on Publication Record
2014
Behavioral Rodent Models of Eating Disorders
KUČEROVÁ, Jana, Zuzana BABINSKÁ and Liana FATTOREBasic information
Original name
Behavioral Rodent Models of Eating Disorders
Name in Czech
Behaviorální hlodavčí modely poruch příjmu potravy
Authors
KUČEROVÁ, Jana (203 Czech Republic, guarantor, belonging to the institution), Zuzana BABINSKÁ (703 Slovakia, belonging to the institution) and Liana FATTORE (380 Italy)
Edition
New York, Appetite, p. 71-96, 26 pp. Human Anatomy and Physiology, 2014
Publisher
Nova Science Publishers
Other information
Language
English
Type of outcome
Kapitola resp. kapitoly v odborné knize
Field of Study
30104 Pharmacology and pharmacy
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
Publication form
electronic version available online
RIV identification code
RIV/00216224:14110/14:00075510
Organization unit
Faculty of Medicine
ISBN
978-1-63117-243-4
Keywords (in Czech)
anorexia nervosa; bulimia nervosa; binging; zvířecí model
Keywords in English
anorexia nervosa; bulimia nervosa; binging; animal model
Tags
Tags
International impact
Změněno: 8/1/2015 15:33, Soňa Böhmová
Abstract
V originále
Eating disorders represent an unmet medical need which implies a serious burden for the patients and their families. While anorexia nervosa and bulimia nervosa are among the most widely reported diseases, the newly published DSM-5 has recently distinguished the – thus far – diagnostically neglected binge-eating disorder as a specific nosologic unit for the first time. Available therapeutic options for the treatment of eating disorders are very limited and generally based on psychological or psychiatric interventions. However, pharmacological research exploiting numerous physiological signaling systems is currently being conducted in order to develop innovative therapies of these disorders. This research calls for a wide range of animal models which must be wisely employed with respect for the purpose of individual studies and the validity of particular models. The objective of this chapter is to provide an overview of well-validated behavioral animal models of anorexia nervosa, bulimia nervosa, binge eating and operant conditioning for natural rewards with special attention dedicated to evidence of face, construct and predictive validities of these models and potential sex-dependent differences.