C 2014

Behavioral Rodent Models of Eating Disorders

KUČEROVÁ, Jana, Zuzana BABINSKÁ and Liana FATTORE

Basic information

Original name

Behavioral Rodent Models of Eating Disorders

Name in Czech

Behaviorální hlodavčí modely poruch příjmu potravy

Authors

KUČEROVÁ, Jana (203 Czech Republic, guarantor, belonging to the institution), Zuzana BABINSKÁ (703 Slovakia, belonging to the institution) and Liana FATTORE (380 Italy)

Edition

New York, Appetite, p. 71-96, 26 pp. Human Anatomy and Physiology, 2014

Publisher

Nova Science Publishers

Other information

Language

English

Type of outcome

Kapitola resp. kapitoly v odborné knize

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Publication form

electronic version available online

RIV identification code

RIV/00216224:14110/14:00075510

Organization unit

Faculty of Medicine

ISBN

978-1-63117-243-4

Keywords (in Czech)

anorexia nervosa; bulimia nervosa; binging; zvířecí model

Keywords in English

anorexia nervosa; bulimia nervosa; binging; animal model

Tags

Tags

International impact
Změněno: 8/1/2015 15:33, Soňa Böhmová

Abstract

V originále

Eating disorders represent an unmet medical need which implies a serious burden for the patients and their families. While anorexia nervosa and bulimia nervosa are among the most widely reported diseases, the newly published DSM-5 has recently distinguished the – thus far – diagnostically neglected binge-eating disorder as a specific nosologic unit for the first time. Available therapeutic options for the treatment of eating disorders are very limited and generally based on psychological or psychiatric interventions. However, pharmacological research exploiting numerous physiological signaling systems is currently being conducted in order to develop innovative therapies of these disorders. This research calls for a wide range of animal models which must be wisely employed with respect for the purpose of individual studies and the validity of particular models. The objective of this chapter is to provide an overview of well-validated behavioral animal models of anorexia nervosa, bulimia nervosa, binge eating and operant conditioning for natural rewards with special attention dedicated to evidence of face, construct and predictive validities of these models and potential sex-dependent differences.

Files attached