KRUŽLIAK, Peter, Jan NOVÁK, Miroslav NOVÁK and George J. FODOR. Role of calprotectin in cardiometabolic diseases. Cytokine & Growth Factor Reviews. Oxford: Elsevier Science Ltd., 2014, vol. 25, No 1, p. 67-75. ISSN 1359-6101. Available from: https://dx.doi.org/10.1016/j.cytogfr.2014.01.005.
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Basic information
Original name Role of calprotectin in cardiometabolic diseases
Authors KRUŽLIAK, Peter (203 Czech Republic, guarantor), Jan NOVÁK (203 Czech Republic, belonging to the institution), Miroslav NOVÁK (203 Czech Republic) and George J. FODOR (124 Canada).
Edition Cytokine & Growth Factor Reviews, Oxford, Elsevier Science Ltd. 2014, 1359-6101.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30105 Physiology
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 5.357
RIV identification code RIV/00216224:14110/14:00075533
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1016/j.cytogfr.2014.01.005
UT WoS 000334082800006
Keywords in English Calprotectin; Cardiovascular diseases; Metabolic diseases; Obesity; Myocardial infarction
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 13/1/2015 15:55.
Abstract
Calprotectin represents an interesting peptide known to be involved in the pathophysiology of various inflammatory processes. Being secreted from activated neutrophils and monocytes under various conditions, it can also be found in the extracellular fluids and serve as a biomarker of ongoing inflammation, which property is currently used in the monitoring of inflammatory bowel diseases. Recent studies, however, suggest that calprotectin could serve as an important prognostic factor for cardiovascular and cardiometabolic diseases, since these are occurring on the basis of low-grade chronic inflammation. We assume that calprotectin may represent a useful marker in predicting the course of atherosclerotic process, coronary artery disease and acute coronary syndromes. Our review is focused on the importance of calprotectin in the diagnosis and prognostic stratification in the field of cardiometabolic risk.
Links
MUNI/A/0957/2013, interní kód MUName: Studium kardiovaskulárních regulací ve zdraví i nemoci (Acronym: SKAREZNEM)
Investor: Masaryk University, Category A
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