| HANÁKOVÁ, Petra, Milan BRÁZDIL, Zdeněk NOVÁK, Jan HEMZA, Jan CHRASTINA, Hana OŠLEJŠKOVÁ, Markéta HERMANOVÁ, Marta PAŽOURKOVÁ, Ivan REKTOR and Robert KUBA. Long-term outcome and predictors of resective surgery prognosis in patients with refractory extratemporal epilepsy. Seizure. Elsevier, 2014, vol. 23, No 4, p. 266-273. ISSN 1059-1311. Available from: https://dx.doi.org/10.1016/j.seizure.2013.12.003. |
Other formats:
BibTeX
LaTeX
RIS
@article{1186438,
author = {Hanáková, Petra and Brázdil, Milan and Novák, Zdeněk and Hemza, Jan and Chrastina, Jan and Ošlejšková, Hana and Hermanová, Markéta and Pažourková, Marta and Rektor, Ivan and Kuba, Robert},
article_number = {4},
doi = {http://dx.doi.org/10.1016/j.seizure.2013.12.003},
keywords = {Epilepsy surgery; Extratemporal; Long-term outcome; Histopathology; Engel's classification},
language = {eng},
issn = {1059-1311},
journal = {Seizure},
title = {Long-term outcome and predictors of resective surgery prognosis in patients with refractory extratemporal epilepsy},
volume = {23},
year = {2014}
}
TY - JOUR
ID - 1186438
AU - Hanáková, Petra - Brázdil, Milan - Novák, Zdeněk - Hemza, Jan - Chrastina, Jan - Ošlejšková, Hana - Hermanová, Markéta - Pažourková, Marta - Rektor, Ivan - Kuba, Robert
PY - 2014
TI - Long-term outcome and predictors of resective surgery prognosis in patients with refractory extratemporal epilepsy
JF - Seizure
VL - 23
IS - 4
SP - 266-273
EP - 266-273
PB - Elsevier
SN - 10591311
KW - Epilepsy surgery
KW - Extratemporal
KW - Long-term outcome
KW - Histopathology
KW - Engel's classification
N2 - Purpose: We analyzed the long-term postoperative outcome and possible predictive factors of the outcome in surgically treated patients with refractory extratemporal epilepsy. Methods: We retrospectively analyzed 73 patients who had undergone resective surgery at the Epilepsy Center Brno between 1995 and 2010 and who had reached at least 1 year outcome after the surgery. The average age at surgery was 28.3 +/- 11.4 years. Magnetic resonance imaging (MRI) did not reveal any lesion in 24 patients (32.9%). Surgical outcome was assessed annually using Engel's modified classification until 5 years after surgery and at the latest follow-up visit. Results: Following the surgery, Engel Class I outcome was found in 52.1% of patients after 1 year, in 55.0% after 5 years, and in 50.7% at the last follow-up visit (average 6.15 +/- 3.84 years). Of the patients who reached the 5-year follow-up visit (average of the last follow-up 9.23 years), 37.5% were classified as Engel IA at each follow-up visit. Tumorous etiology and lesions seen in preoperative MRI were associated with significantly better outcome (p = 0.035; p < 0.01). Postoperatively, 9.6% patients had permanent neurological deficits. Conclusion: Surgical treatment of refractory extratemporal epilepsy is an effective procedure. The presence of a visible MRI-detected lesion and tumorous etiology is associated with significantly better outcome than the absence of MRI-detected lesion or other etiology.
ER -
HANÁKOVÁ, Petra, Milan BRÁZDIL, Zdeněk NOVÁK, Jan HEMZA, Jan CHRASTINA, Hana OŠLEJŠKOVÁ, Markéta HERMANOVÁ, Marta PAŽOURKOVÁ, Ivan REKTOR and Robert KUBA. Long-term outcome and predictors of resective surgery prognosis in patients with refractory extratemporal epilepsy. \textit{Seizure}. Elsevier, 2014, vol.~23, No~4, p.~266-273. ISSN~1059-1311. Available from: https://dx.doi.org/10.1016/j.seizure.2013.12.003.
|
